PTPRK expression in EBV-positive and EBV-negative primary HL
| PTPRK status of HRS cells . | EBV positive . | EBV negative . |
|---|---|---|
| PTPRKhi | 6 | 26 |
| PTPRKlow or negative | 13 | 8 |
| Percentage of cases with low or negative PTPRK expression, % (n/N) | 68.4 (13/19) | 23.5 (8/34) |
| PTPRK status of HRS cells . | EBV positive . | EBV negative . |
|---|---|---|
| PTPRKhi | 6 | 26 |
| PTPRKlow or negative | 13 | 8 |
| Percentage of cases with low or negative PTPRK expression, % (n/N) | 68.4 (13/19) | 23.5 (8/34) |
Staining in tumor cells assessed as either negative or lower than surrounding lymphocytes (PTPRKlow) or equivalent to or higher than surrounding lymphocytes (PTPRKhi). PTPRKlow cases are significantly more frequent in the EBV-positive group (P value of Fisher exact test is .003).
n indicates the number of affected cases; and N, the number of total cases within group.