Notch inhibition improves kidney disease
| Disease parameter . | DAPT-treated, average score (range) . | Control, average score (range) . | P . |
|---|---|---|---|
| Medullary LP | 1.8 (1-3) | 3.3 (2-4) | .02 |
| Cortical LP | 1.5 (0-4) | 3 (2-4) | .05 |
| Glomerulonephritis | 1 (0-2) | 3.8 (3-5) | .002 |
| Nephropathy | 0.3 (0-1) | 1 (0-2) | .1 |
| Nephritis index | 4.6 (1-10) | 11 (10-14) | .007 |
| Disease parameter . | DAPT-treated, average score (range) . | Control, average score (range) . | P . |
|---|---|---|---|
| Medullary LP | 1.8 (1-3) | 3.3 (2-4) | .02 |
| Cortical LP | 1.5 (0-4) | 3 (2-4) | .05 |
| Glomerulonephritis | 1 (0-2) | 3.8 (3-5) | .002 |
| Nephropathy | 0.3 (0-1) | 1 (0-2) | .1 |
| Nephritis index | 4.6 (1-10) | 11 (10-14) | .007 |
Data are index levels, which were scored as follows: 0 indicates normal; 1, minimal; 2, mild; 3, moderate; 4, marked; 5, severe.
LP indicates lymphoid proliferation.