Table 2

Patients and alemtuzumab doses per regimen

Single agent/RegimenNo. of patientsAlemtuzumab, no. doses/monthMaximum doses
MRD 12 12 
Therapy 12 36 
    + Rituximab 12 12 
    + Pentostatin 12 36 
    + FCR 23 18 
    + Hyper CVAD 
    + MTX/asparaginase 
Single agent/RegimenNo. of patientsAlemtuzumab, no. doses/monthMaximum doses
MRD 12 12 
Therapy 12 36 
    + Rituximab 12 12 
    + Pentostatin 12 36 
    + FCR 23 18 
    + Hyper CVAD 
    + MTX/asparaginase 

MRD indicates minimal residual disease; FCR, fludarabine, cyclophosphamide, rituximab; CVAD, fractionated cyclophosphamide, vincristine, cytarabine, and dexamethasone; MTX, methotrexate.

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