Table 2

Cell counts in spleen and BM

Tissue/genotypeCell count, × 107Red cells, × 108Platelets, × 108
Spleen/control 1.7 ± 0.2* 4.9 ± 0.3* 5.8 ± 0.5* 
Spleen/Vav-Cre Rb KO 6.0 ± 0.3* 15.5 ± 3.4* 37.2 ± 6.4* 
BM/control 8.3 ± 0.8 19.0 ± 2.4 ND 
BM/Vav-Cre Rb KO 7.9 ± 0.4 11.7 ± 1.1 ND 
Tissue/genotypeCell count, × 107Red cells, × 108Platelets, × 108
Spleen/control 1.7 ± 0.2* 4.9 ± 0.3* 5.8 ± 0.5* 
Spleen/Vav-Cre Rb KO 6.0 ± 0.3* 15.5 ± 3.4* 37.2 ± 6.4* 
BM/control 8.3 ± 0.8 19.0 ± 2.4 ND 
BM/Vav-Cre Rb KO 7.9 ± 0.4 11.7 ± 1.1 ND 

ND indicates not determined. Shown are mean values plus or minus 1 SEM. Total cell counts in BM are based on tibia and femur combined. n = 5 for controls and n = 6 for Vav-Cre Rb KO animals.

*

Significantly different between control and Vav-Cre Rb KO animals (P < .05).

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