Table 2

Engraftment of donor-derived cells in the injured liver of mice transplanted with either clonal cells from KSL-CD34 cells or BM TNCs

Cells transplantedCells
CD45+ cells in EGFP+ cells, %
EGFP+ cellsEGFP+CD45+ cells
Clonal cells    
    1 33.1 ± 9.9 12.6 ± 2.5 38.1 
    2 42.1 ± 9.8 20.0 ± 3.8 47.5 
    3 12.0 ± 3.4 6.3 ± 0.9 52.5 
BM TNCs    
    1 31.6 ± 6.6 11.5 ± 3.9 37.6 
    2 29.2 ± 10.2 14.9 ± 4.2 51.0 
    3 25.9 ± 5.1 12.2 ± 2.5 47.1 
Cells transplantedCells
CD45+ cells in EGFP+ cells, %
EGFP+ cellsEGFP+CD45+ cells
Clonal cells    
    1 33.1 ± 9.9 12.6 ± 2.5 38.1 
    2 42.1 ± 9.8 20.0 ± 3.8 47.5 
    3 12.0 ± 3.4 6.3 ± 0.9 52.5 
BM TNCs    
    1 31.6 ± 6.6 11.5 ± 3.9 37.6 
    2 29.2 ± 10.2 14.9 ± 4.2 51.0 
    3 25.9 ± 5.1 12.2 ± 2.5 47.1 

Sections of livers from transplanted mice were stained for CD45. EGFP+ cells and EGFP+CD45+ cells were counted as described in “Immunohistochemical analysis” as the number of positive cells in each high-power field. Data represent the mean numbers of cells plus or minus the standard deviation or the percentage of CD45+ cells in EGFP+ cells.

KSL indicates LinSca-1+c-kit+.

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