Engraftment of donor-derived cells in the injured liver of mice transplanted with either clonal cells from KSL-CD34− cells or BM TNCs
Cells transplanted . | Cells . | CD45+ cells in EGFP+ cells, % . | |
---|---|---|---|
EGFP+ cells . | EGFP+CD45+ cells . | ||
Clonal cells | |||
1 | 33.1 ± 9.9 | 12.6 ± 2.5 | 38.1 |
2 | 42.1 ± 9.8 | 20.0 ± 3.8 | 47.5 |
3 | 12.0 ± 3.4 | 6.3 ± 0.9 | 52.5 |
BM TNCs | |||
1 | 31.6 ± 6.6 | 11.5 ± 3.9 | 37.6 |
2 | 29.2 ± 10.2 | 14.9 ± 4.2 | 51.0 |
3 | 25.9 ± 5.1 | 12.2 ± 2.5 | 47.1 |
Cells transplanted . | Cells . | CD45+ cells in EGFP+ cells, % . | |
---|---|---|---|
EGFP+ cells . | EGFP+CD45+ cells . | ||
Clonal cells | |||
1 | 33.1 ± 9.9 | 12.6 ± 2.5 | 38.1 |
2 | 42.1 ± 9.8 | 20.0 ± 3.8 | 47.5 |
3 | 12.0 ± 3.4 | 6.3 ± 0.9 | 52.5 |
BM TNCs | |||
1 | 31.6 ± 6.6 | 11.5 ± 3.9 | 37.6 |
2 | 29.2 ± 10.2 | 14.9 ± 4.2 | 51.0 |
3 | 25.9 ± 5.1 | 12.2 ± 2.5 | 47.1 |
Sections of livers from transplanted mice were stained for CD45. EGFP+ cells and EGFP+CD45+ cells were counted as described in “Immunohistochemical analysis” as the number of positive cells in each high-power field. Data represent the mean numbers of cells plus or minus the standard deviation or the percentage of CD45+ cells in EGFP+ cells.
KSL indicates Lin−Sca-1+c-kit+.