Table 1 Hematologic parameters and TPO... | American Society of Hematology

Table 1

Hematologic parameters and TPO plasma levels

	Plt, × 10⁶/L	MPV, fL	WBC, × 10⁶/L	RBC, × 10⁹/L	Hct, L/L	Hgb, g/L	TPO, pg/mL
Normal human values, range	150–450	9.0–13.0	4.0–10.0	4.5–6.0	0.4–0.54	140–180	ND-196
PACAP-overexpressing patient 1	68, 90	8.2, 8.0	8.0, 9.8	4.31, 4.37	0.37, 0.36	121, 126	54, 86
PACAP-overexpressing patient 2	99	8.2	6.3	5.24	0.42	148	NA
Normal FVB mice (n=20)	785 ± 75	NA	4.3 ± 1.2	7.1 ± 0.4	0.3 ± 0.02	115 ± 9	106 ± 77
PACAPTG9-FVB (n=20)	636 ± 42*	NA	3.3 ± 1.1†	6.9 ± 0.3	0.3 ± 0.01	113 ± 6	136 ± 54

	Plt, × 10⁶/L	MPV, fL	WBC, × 10⁶/L	RBC, × 10⁹/L	Hct, L/L	Hgb, g/L	TPO, pg/mL
Normal human values, range	150–450	9.0–13.0	4.0–10.0	4.5–6.0	0.4–0.54	140–180	ND-196
PACAP-overexpressing patient 1	68, 90	8.2, 8.0	8.0, 9.8	4.31, 4.37	0.37, 0.36	121, 126	54, 86
PACAP-overexpressing patient 2	99	8.2	6.3	5.24	0.42	148	NA
Normal FVB mice (n=20)	785 ± 75	NA	4.3 ± 1.2	7.1 ± 0.4	0.3 ± 0.02	115 ± 9	106 ± 77
PACAPTG9-FVB (n=20)	636 ± 42*	NA	3.3 ± 1.1†	6.9 ± 0.3	0.3 ± 0.01	113 ± 6	136 ± 54

Values for patient 1 were measured on different occasions. Values are means plus or minus SD.

Plt indicates platelets; MPV, mean platelet volume; WBC, white blood cells; RBC, red blood cells; Hct, hematocrit; Hgb, hemoglobin; NA, not available; and ND, not detectable.

P < .001.

†

P = .003.

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