Demographic data for the entire cohort of septic patients and age- and gender-matched healthy donors
| Characteristics . | Healthy donors (n = 52) . | Septic patients (n = 118) . | P . |
|---|---|---|---|
| Age, mean ± standard deviation, y | 53.6 ± 21.7 | 54.7 ± 18.1 | .63 |
| Sex (male), n (%) | 15 (36) | 38 (44.7) | .72 |
| Shock, n (%) | — | 62 (54.8) | — |
| Mechanical ventilation, n (%) | — | 70 (61.9) | — |
| 28-d mortality, n (%) | — | 30 (26.5) | — |
| Platelets, mean ± standard deviation, ×109/L | 287 ± 59 | 186 ± 92 | <.0001 |
| Characteristics . | Healthy donors (n = 52) . | Septic patients (n = 118) . | P . |
|---|---|---|---|
| Age, mean ± standard deviation, y | 53.6 ± 21.7 | 54.7 ± 18.1 | .63 |
| Sex (male), n (%) | 15 (36) | 38 (44.7) | .72 |
| Shock, n (%) | — | 62 (54.8) | — |
| Mechanical ventilation, n (%) | — | 70 (61.9) | — |
| 28-d mortality, n (%) | — | 30 (26.5) | — |
| Platelets, mean ± standard deviation, ×109/L | 287 ± 59 | 186 ± 92 | <.0001 |
Demographic data from septic patients were collected at the time of study enrollment, which was within 48 (±24) hours of ICU admission for sepsis. Shock was defined as the need for vasoactive medications to maintain a mean arterial pressure >65 mm Hg.