Table 2. Cardiac and laboratory... | American Society of Hematology

Table 2.

Cardiac and laboratory parameters before and following HSCT in 44 patients with successful transplants

Parameter	Baseline	3 mo	6 mo	1 y
BSA, m²	1.87 ± 0.21	1.87 ± 0.23	1.89 ± 0.22^	1.92 ± 0.23***
SBP, mm Hg	120 ± 14	123 ± 12	122 ± 15	121 ± 16
DBP, mm Hg	64 ± 12	71 ± 10***	72 ± 10***	71 ± 12*
Heart rate, beats/min	75 ± 14	74 ± 13	78 ± 15	76 ± 15
TR, cm/s	2.6 ± 0.34	2.5 ± 0.20	2.5 ± 0.27	2.4 ± 0.29*
RVSP, mm Hg	33 ± 7.2	30 ± 4.4	31 ± 5.8	29 ± 5.5
LVEDD, mm	51 ± 4.9	49 ± 4.6*	48 ± 4.8***	48 ± 4.9***
LVESD, mm	33 ± 4.2	34 ± 5.3	33 ± 6.5	33 ± 4.0
LVEDV/BSA, mL/m²	83 ± 22	69 ± 21***	68 ± 20***	65 ± 18***
LV mass index, g/m²	101 ± 27	90 ± 25	86 ± 25***	89 ± 22**
LA volume index, mL/m²	46 ± 14	36 ± 18*	38 ± 15***	36 ± 12***
EF, %	65 ± 4.9	57 ± 5.1***	58 ± 6.1***	60 ± 5.2***
CO, L/min	6.1 ± 1.9	5.1 ± 1.2	5.7 ± 1.6	5.6 ± 1.9
E/A ratio	1.7 ± 0.6	1.5 ± 0.5	1.4 ± 0.5*	1.5 ± 0.5
Sep E/e′, cm/s	10.8 ± 2.6	9.3 ± 2.3***	8.7 ± 2.0***	9.1 ± 2.0***
Lat E/e′, cm/s	16 ± 3.9	15 ± 4.6	14 ± 4.2	14 ± 3.2*
Hemoglobin, g/dL	9.5 ± 0.9	11.3 ± 2.0***	11.7 ± 2.1***	12.3 ± 1.9***
Total bilirubin, mg/dL	2.1 ± 3.1	0.4 ± 0.3***	0.6 ± 0.3***	0.5 ± 0.3***
Serum creatinine, mg/dL	1.0 ± 1.5	1.4 ± 2.3***	1.5 ± 3.1***	1.4 ± 2.8***
Reticulocyte count, %	3.5 ± 2.8	2.1 ± 1.5***	2.2 ± 1.3	2.0 ± 1.2
LDH, U/L	338 ± 122	248 ± 80***	253 ± 127***	208 ± 61***^,^^
6-min walk, m	509 ± 81	501 ± 98	525 ± 113	544 ± 83**

Parameter	Baseline	3 mo	6 mo	1 y
BSA, m²	1.87 ± 0.21	1.87 ± 0.23	1.89 ± 0.22^	1.92 ± 0.23***
SBP, mm Hg	120 ± 14	123 ± 12	122 ± 15	121 ± 16
DBP, mm Hg	64 ± 12	71 ± 10***	72 ± 10***	71 ± 12*
Heart rate, beats/min	75 ± 14	74 ± 13	78 ± 15	76 ± 15
TR, cm/s	2.6 ± 0.34	2.5 ± 0.20	2.5 ± 0.27	2.4 ± 0.29*
RVSP, mm Hg	33 ± 7.2	30 ± 4.4	31 ± 5.8	29 ± 5.5
LVEDD, mm	51 ± 4.9	49 ± 4.6*	48 ± 4.8***	48 ± 4.9***
LVESD, mm	33 ± 4.2	34 ± 5.3	33 ± 6.5	33 ± 4.0
LVEDV/BSA, mL/m²	83 ± 22	69 ± 21***	68 ± 20***	65 ± 18***
LV mass index, g/m²	101 ± 27	90 ± 25	86 ± 25***	89 ± 22**
LA volume index, mL/m²	46 ± 14	36 ± 18*	38 ± 15***	36 ± 12***
EF, %	65 ± 4.9	57 ± 5.1***	58 ± 6.1***	60 ± 5.2***
CO, L/min	6.1 ± 1.9	5.1 ± 1.2	5.7 ± 1.6	5.6 ± 1.9
E/A ratio	1.7 ± 0.6	1.5 ± 0.5	1.4 ± 0.5*	1.5 ± 0.5
Sep E/e′, cm/s	10.8 ± 2.6	9.3 ± 2.3***	8.7 ± 2.0***	9.1 ± 2.0***
Lat E/e′, cm/s	16 ± 3.9	15 ± 4.6	14 ± 4.2	14 ± 3.2*
Hemoglobin, g/dL	9.5 ± 0.9	11.3 ± 2.0***	11.7 ± 2.1***	12.3 ± 1.9***
Total bilirubin, mg/dL	2.1 ± 3.1	0.4 ± 0.3***	0.6 ± 0.3***	0.5 ± 0.3***
Serum creatinine, mg/dL	1.0 ± 1.5	1.4 ± 2.3***	1.5 ± 3.1***	1.4 ± 2.8***
Reticulocyte count, %	3.5 ± 2.8	2.1 ± 1.5***	2.2 ± 1.3	2.0 ± 1.2
LDH, U/L	338 ± 122	248 ± 80***	253 ± 127***	208 ± 61***^,^^
6-min walk, m	509 ± 81	501 ± 98	525 ± 113	544 ± 83**

P ≤ .05, **P ≤ .01, ***P ≤ .005 for follow-up studies compared with baseline echo.

^{^}

P ≤ .05 and ^^P ≤ .01 for 3- vs 6-month studies and 6 vs 12 months.