Table 5.

Results that “rule-in” or “rule-out” PE

Results
Diagnostic for PE 
CTPA 
 Intraluminal filling defect in a lobar or main pulmonary artery 
 Intraluminal filling defect in a segmental pulmonary artery AND moderate or high CPTP 
V/Q scan 
 High-probability scan AND moderate or high CPTP 
Positive diagnostic test for DVT (with a nondiagnostic V/Q scan or CTPA, or scan not done) 
Rules-out PE 
CTPA 
 Negative good quality scan 
Perfusion scan (usually part of V/Q scan) 
 Normal 
D-dimer 
 Negative very sensitive test (eg, D-dimer <500 μg/L) AND low or moderate CPTP 
 Negative moderately sensitive test AND low CPTP 
 In patients over 50 y, D-dimer level <10 times the patient's age AND a low or moderate CPTP 
Nondiagnostic V/Q scan or CTPA AND normal proximal venous US AND one of: 
 Low CPTP 
 Negative moderately or very sensitive D-dimer test 
 Normal repeat proximal US after 7 d and 14 d 
Results
Diagnostic for PE 
CTPA 
 Intraluminal filling defect in a lobar or main pulmonary artery 
 Intraluminal filling defect in a segmental pulmonary artery AND moderate or high CPTP 
V/Q scan 
 High-probability scan AND moderate or high CPTP 
Positive diagnostic test for DVT (with a nondiagnostic V/Q scan or CTPA, or scan not done) 
Rules-out PE 
CTPA 
 Negative good quality scan 
Perfusion scan (usually part of V/Q scan) 
 Normal 
D-dimer 
 Negative very sensitive test (eg, D-dimer <500 μg/L) AND low or moderate CPTP 
 Negative moderately sensitive test AND low CPTP 
 In patients over 50 y, D-dimer level <10 times the patient's age AND a low or moderate CPTP 
Nondiagnostic V/Q scan or CTPA AND normal proximal venous US AND one of: 
 Low CPTP 
 Negative moderately or very sensitive D-dimer test 
 Normal repeat proximal US after 7 d and 14 d 
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