Laboratory evaluation of thrombocytopenia in pregnancy
| Evaluation . | Tests . |
|---|---|
| Recommended tests | Complete blood count |
| Peripheral blood smear review | |
| Direct antiglobulin (Coombs) test (DAT) | |
| Reticulocyte count | |
| Liver function tests | |
| Viral screen (HIV, HCV, HBV, CMV) | |
| Creatinine | |
| Consider testing | Antinuclear antibody |
| Antiphospholipid antibodies, lupus anticoagulant | |
| Thyroid function tests | |
| Helicobacter pylori (stool antigen or breath test) | |
| Coagulation testing | |
| Quantitative immunoglobulins | |
| VWD panel (for VWF type 2b) | |
| ADAMTS-13 level | |
| Not routinely recommended | Antiplatelet antibody |
| Bone marrow aspiration | |
| Peripheral blood flow cytometry | |
| Thrombopoietin level |
| Evaluation . | Tests . |
|---|---|
| Recommended tests | Complete blood count |
| Peripheral blood smear review | |
| Direct antiglobulin (Coombs) test (DAT) | |
| Reticulocyte count | |
| Liver function tests | |
| Viral screen (HIV, HCV, HBV, CMV) | |
| Creatinine | |
| Consider testing | Antinuclear antibody |
| Antiphospholipid antibodies, lupus anticoagulant | |
| Thyroid function tests | |
| Helicobacter pylori (stool antigen or breath test) | |
| Coagulation testing | |
| Quantitative immunoglobulins | |
| VWD panel (for VWF type 2b) | |
| ADAMTS-13 level | |
| Not routinely recommended | Antiplatelet antibody |
| Bone marrow aspiration | |
| Peripheral blood flow cytometry | |
| Thrombopoietin level |
CMV, cytomegalovirus; HBV, hepatitis B virus; HCV, hepatitis C virus.