Distribution of complications related to iron overload in both TDT and NTDT
| . | Complications* . | |
|---|---|---|
| TDT . | NTDT . | |
| Cardiovascular | Cardiac siderosis, left ventricular heart failure | Pulmonary hypertension, right ventricular heart failure, venous thrombosis |
| Liver | Liver fibrosis, liver cirrhosis, viral hepatitis | Liver fibrosis, liver cirrhosis, hepatocellular carcinoma |
| Endocrine | Hypothyroidism, hypoparathyroidism, growth retardation, hypogonadism, osteoporosis, diabetes mellitus | Osteoporosis |
| Other | Leg ulcers, gallstones, extramedullary hematopoietic tumors, silent cerebral ischemia | |
| . | Complications* . | |
|---|---|---|
| TDT . | NTDT . | |
| Cardiovascular | Cardiac siderosis, left ventricular heart failure | Pulmonary hypertension, right ventricular heart failure, venous thrombosis |
| Liver | Liver fibrosis, liver cirrhosis, viral hepatitis | Liver fibrosis, liver cirrhosis, hepatocellular carcinoma |
| Endocrine | Hypothyroidism, hypoparathyroidism, growth retardation, hypogonadism, osteoporosis, diabetes mellitus | Osteoporosis |
| Other | Leg ulcers, gallstones, extramedullary hematopoietic tumors, silent cerebral ischemia | |
All complications can happen in both TDT and NTDT. This table mentions the distribution of the more commonly prevalent complications in each group based on available studies.