Chemokines mentioned in this review together with their alternative names, according to a recent classification system, and their receptors
| Traditional name . | Alternative designation . | Chemokine receptor . |
|---|---|---|
| CXC family of chemokines | ||
| GRO/MGSA | CXCL1 | CXCR2 > CXCR1 |
| IL-8 | CXCL8 | CXCR1, CXCR2 |
| IP-10 | CXCL10 | CXCR3 |
| MIG | CXCL9 | CXCR3 |
| NAP-2 | CXCL7 | CXCR2 |
| PF4 | CXCL4 | Unknown |
| SDF-1 | CXCL12 | CXCR4 |
| CC family of chemokines | ||
| ELC | CCL19 | CCR7 |
| I-309 | CCL1 | CCR8 |
| MCP-1 | CCL2 | CCR2 |
| MIP-1α | CCL3 | CCR1, CCR5 |
| MIP-1β | CCL4 | CCR5 |
| RANTES | CCL5 | CCR1, CCR3, CCR5 |
| C family of chemokines | ||
| Lymphotactin | XCL1 | XCR1 |
| CX3C family of chemokines | ||
| Fractalkine | CX3CL1 | CX3CR1 |
| Traditional name . | Alternative designation . | Chemokine receptor . |
|---|---|---|
| CXC family of chemokines | ||
| GRO/MGSA | CXCL1 | CXCR2 > CXCR1 |
| IL-8 | CXCL8 | CXCR1, CXCR2 |
| IP-10 | CXCL10 | CXCR3 |
| MIG | CXCL9 | CXCR3 |
| NAP-2 | CXCL7 | CXCR2 |
| PF4 | CXCL4 | Unknown |
| SDF-1 | CXCL12 | CXCR4 |
| CC family of chemokines | ||
| ELC | CCL19 | CCR7 |
| I-309 | CCL1 | CCR8 |
| MCP-1 | CCL2 | CCR2 |
| MIP-1α | CCL3 | CCR1, CCR5 |
| MIP-1β | CCL4 | CCR5 |
| RANTES | CCL5 | CCR1, CCR3, CCR5 |
| C family of chemokines | ||
| Lymphotactin | XCL1 | XCR1 |
| CX3C family of chemokines | ||
| Fractalkine | CX3CL1 | CX3CR1 |
The current classification system is described by Zlotnik and Yoshie.107
GRO indicates growth-regulated gene product; MGSA, melanoma growth-stimulatory activity; IP, interferon-inducible protein; MIG, monokine-induced by interferon γ; NAP, neutrophil-activating protein; PF, platelet factor; SDF, stromal cell-derived factor; ELC, EBII-ligand chemokine; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; RANTES, regulated upon activation, normal T cell expressed and secreted; and CXCR, CXC receptor.