Results of multivariate Cox analysis for potential effect on TRM
| Variable . | Baseline value . | Compared value . | RR (95% CI) . | P . |
|---|---|---|---|---|
| Cell dose | ≤ 2.4 × 108/kg | > 2.4 × 108/kg and ≤ 5 × 108/kg | 0.76 (0.58-0.99) | |
| > 5 × 108/kg | 0.6 (0.41-0.88) | .002 | ||
| Donor type | HLA-identical sibling | Alternative | 2.19 (1.61-2.97) | .0001 |
| Year of transplantation | 1987 or before | 1997 or before | 0.44 (0.33-0.6) | |
| After 1997 | 0.32 (0.21-0.5) | .0001 | ||
| Conditioning regimen | TBI: yes | TBI: no | 1.36 (1.04-1.77) | .02 |
| Recipient age | ≤ 30 y | > 30 y | 1.02 (1.00-1.03) | .02 |
| Donor age | ≤ 31 y | > 31 y | 1.01 (1.00-1.02) | .06 |
| Disease phase | Early | Advanced | 1.25 (0.99-1.59) | .06 |
| Variable . | Baseline value . | Compared value . | RR (95% CI) . | P . |
|---|---|---|---|---|
| Cell dose | ≤ 2.4 × 108/kg | > 2.4 × 108/kg and ≤ 5 × 108/kg | 0.76 (0.58-0.99) | |
| > 5 × 108/kg | 0.6 (0.41-0.88) | .002 | ||
| Donor type | HLA-identical sibling | Alternative | 2.19 (1.61-2.97) | .0001 |
| Year of transplantation | 1987 or before | 1997 or before | 0.44 (0.33-0.6) | |
| After 1997 | 0.32 (0.21-0.5) | .0001 | ||
| Conditioning regimen | TBI: yes | TBI: no | 1.36 (1.04-1.77) | .02 |
| Recipient age | ≤ 30 y | > 30 y | 1.02 (1.00-1.03) | .02 |
| Donor age | ≤ 31 y | > 31 y | 1.01 (1.00-1.02) | .06 |
| Disease phase | Early | Advanced | 1.25 (0.99-1.59) | .06 |
TRM indicates transplant-related mortality; RR, relative risk; CI, confidence interval; and TBI, total body irradiation.