Correlation of BCL-2 expression in HRS cells with clinical and laboratory findings
| Parameter . | All patients . | BCL-2+ . | P3-150 . | |
|---|---|---|---|---|
| No. . | % . | |||
| Age, y | ||||
| 45 or older | 143 | 72 | 50 | .003 |
| Younger than 45 | 564 | 323 | 64 | |
| Sex | ||||
| Male | 383 | 217 | 57 | .005 |
| Female | 324 | 217 | 67 | |
| Stage | ||||
| I | 94 | 50 | 53 | .008 |
| II | 358 | 238 | 66 | |
| III | 142 | 74 | 52 | |
| IV | 113 | 72 | 64 | |
| B symptoms | ||||
| Present | 258 | 173 | 68 | .02 |
| Absent | 449 | 261 | 58 | |
| Serum albumin level | ||||
| Low3-151 | 96 | 64 | 67 | .3 |
| Normal | 552 | 336 | 61 | |
| Anemia | ||||
| Present | 313 | 198 | 63 | .4 |
| Absent | 389 | 232 | 60 | |
| Leukocytosis3-152 | ||||
| Present | 67 | 48 | 72 | .09 |
| Absent | 635 | 383 | 60 | |
| Lymphocytopenia3-152 | ||||
| Present | 63 | 40 | 63 | .7 |
| Absent | 574 | 347 | 60 | |
| Serum β2-microglobulin level | ||||
| High3-151 | 161 | 92 | 57 | .3 |
| Normal | 273 | 172 | 63 | |
| Serum LDH level | ||||
| High3-151 | 213 | 139 | 65 | .17 |
| Normal | 414 | 246 | 59 | |
| Bone marrow involvement | ||||
| Present | 55 | 29 | 53 | .2 |
| Absent | 652 | 405 | 62 | |
| Mediastinal mass ratio | ||||
| At least 0.45 | 77 | 52 | 68 | .2 |
| Lower than 0.45 | 425 | 254 | 60 | |
| Inguinal or iliac nodes | ||||
| Involved | 131 | 79 | 60 | .8 |
| Uninvolved | 574 | 354 | 62 | |
| Parameter . | All patients . | BCL-2+ . | P3-150 . | |
|---|---|---|---|---|
| No. . | % . | |||
| Age, y | ||||
| 45 or older | 143 | 72 | 50 | .003 |
| Younger than 45 | 564 | 323 | 64 | |
| Sex | ||||
| Male | 383 | 217 | 57 | .005 |
| Female | 324 | 217 | 67 | |
| Stage | ||||
| I | 94 | 50 | 53 | .008 |
| II | 358 | 238 | 66 | |
| III | 142 | 74 | 52 | |
| IV | 113 | 72 | 64 | |
| B symptoms | ||||
| Present | 258 | 173 | 68 | .02 |
| Absent | 449 | 261 | 58 | |
| Serum albumin level | ||||
| Low3-151 | 96 | 64 | 67 | .3 |
| Normal | 552 | 336 | 61 | |
| Anemia | ||||
| Present | 313 | 198 | 63 | .4 |
| Absent | 389 | 232 | 60 | |
| Leukocytosis3-152 | ||||
| Present | 67 | 48 | 72 | .09 |
| Absent | 635 | 383 | 60 | |
| Lymphocytopenia3-152 | ||||
| Present | 63 | 40 | 63 | .7 |
| Absent | 574 | 347 | 60 | |
| Serum β2-microglobulin level | ||||
| High3-151 | 161 | 92 | 57 | .3 |
| Normal | 273 | 172 | 63 | |
| Serum LDH level | ||||
| High3-151 | 213 | 139 | 65 | .17 |
| Normal | 414 | 246 | 59 | |
| Bone marrow involvement | ||||
| Present | 55 | 29 | 53 | .2 |
| Absent | 652 | 405 | 62 | |
| Mediastinal mass ratio | ||||
| At least 0.45 | 77 | 52 | 68 | .2 |
| Lower than 0.45 | 425 | 254 | 60 | |
| Inguinal or iliac nodes | ||||
| Involved | 131 | 79 | 60 | .8 |
| Uninvolved | 574 | 354 | 62 | |