Univariate statistical analysis of prognostic factors for patients with cHD treated with ABVD or equivalent regimens
| Factor . | No. of patients . | % 5-y FFS . | P5-150 . |
|---|---|---|---|
| Age, y | 997 | .005 | |
| 45 or older | 73 | ||
| Younger than 45 | 82 | ||
| Sex | 997 | .5 | |
| Male | 80 | ||
| Female | 81 | ||
| Stage | 997 | <.0001 | |
| I-III | 85 | ||
| IV | 63 | ||
| B symptoms | 997 | <.0001 | |
| Present | 73 | ||
| Absent | 86 | ||
| Serum albumin level | 821 | <.0001 | |
| Low5-151 | 67 | ||
| Normal | 83 | ||
| Anemia | 983 | <.0001 | |
| Present | 76 | ||
| Absent | 86 | ||
| Leukocytosis5-152 | 980 | .0006 | |
| Present | 70 | ||
| Absent | 82 | ||
| Lymphocytopenia5-152 | 840 | .02 | |
| Present | 71 | ||
| Absent | 80 | ||
| Serum β2-microglobulin level | 486 | .0008 | |
| High5-151 | 73 | ||
| Normal | 85 | ||
| Serum LDH level | 731 | .004 | |
| High5-151 | 76 | ||
| Normal | 84 | ||
| Bone marrow involvement | 996 | <.0001 | |
| Present | 62 | ||
| Absent | 82 | ||
| Mediastinal mass ratio | 436 | .9 | |
| At least 0.45 | 80 | ||
| Lower than 0.45 | 80 | ||
| Inguinal or iliac nodes | 987 | <.0001 | |
| Involved | 70 | ||
| Uninvolved | 84 | ||
| BCL-2 | 412 | .001 | |
| Positive | 74 | ||
| Negative | 88 |
| Factor . | No. of patients . | % 5-y FFS . | P5-150 . |
|---|---|---|---|
| Age, y | 997 | .005 | |
| 45 or older | 73 | ||
| Younger than 45 | 82 | ||
| Sex | 997 | .5 | |
| Male | 80 | ||
| Female | 81 | ||
| Stage | 997 | <.0001 | |
| I-III | 85 | ||
| IV | 63 | ||
| B symptoms | 997 | <.0001 | |
| Present | 73 | ||
| Absent | 86 | ||
| Serum albumin level | 821 | <.0001 | |
| Low5-151 | 67 | ||
| Normal | 83 | ||
| Anemia | 983 | <.0001 | |
| Present | 76 | ||
| Absent | 86 | ||
| Leukocytosis5-152 | 980 | .0006 | |
| Present | 70 | ||
| Absent | 82 | ||
| Lymphocytopenia5-152 | 840 | .02 | |
| Present | 71 | ||
| Absent | 80 | ||
| Serum β2-microglobulin level | 486 | .0008 | |
| High5-151 | 73 | ||
| Normal | 85 | ||
| Serum LDH level | 731 | .004 | |
| High5-151 | 76 | ||
| Normal | 84 | ||
| Bone marrow involvement | 996 | <.0001 | |
| Present | 62 | ||
| Absent | 82 | ||
| Mediastinal mass ratio | 436 | .9 | |
| At least 0.45 | 80 | ||
| Lower than 0.45 | 80 | ||
| Inguinal or iliac nodes | 987 | <.0001 | |
| Involved | 70 | ||
| Uninvolved | 84 | ||
| BCL-2 | 412 | .001 | |
| Positive | 74 | ||
| Negative | 88 |