Patients, disease, and transplantation characteristics
| Characteristics . | n = 107 . |
|---|---|
| Recipient | |
| Median age, y (range) | 35 (3-56) |
| Median weight, kg (range) | 65 (15-126) |
| Male (%) | 67 (63) |
| Children, 15 y or younger (%) | 17 (16) |
| Positive CMV serology (%) | 46 (43) |
| Underlying diagnosis | |
| Chronic leukemia (%) | 68 (64) |
| Acute leukemia (%) | 39 (36) |
| Disease stage | |
| Early (%) | 82 (77) |
| Intermediate (%) | 20 (19) |
| Advanced (%) | 5 (5) |
| Donor | |
| Median age, y (range) | 34 (2-65) |
| Male (%) | 56 (52) |
| Female donor to male recipient (%) | 31 (29) |
| Sex match (%) | 56 (52) |
| ABO match (%) | 72 (67) |
| ABO major incompatibility (%) | 17 (16) |
| Positive CMV serology (%) | 56 (55) |
| Transplantation | |
| Conditioning | |
| TBI + CY ± others (%) | 32 (30) |
| Bu + CY (%) | 58 (54) |
| GVHD prophylaxis | |
| CSA + MTX (%) | 94 (88) |
| CSA + MTX + other (%) | 6 (6) |
| CSA ± corticosteroids (%) | 7 (6) |
| Graft composition | |
| Median NC, 108/kg (range) | 2.4 (0.2-8.1) |
| Median CD34, 106/kg (range) n = 83 | 3.6 (0.07-17.9) |
| Characteristics . | n = 107 . |
|---|---|
| Recipient | |
| Median age, y (range) | 35 (3-56) |
| Median weight, kg (range) | 65 (15-126) |
| Male (%) | 67 (63) |
| Children, 15 y or younger (%) | 17 (16) |
| Positive CMV serology (%) | 46 (43) |
| Underlying diagnosis | |
| Chronic leukemia (%) | 68 (64) |
| Acute leukemia (%) | 39 (36) |
| Disease stage | |
| Early (%) | 82 (77) |
| Intermediate (%) | 20 (19) |
| Advanced (%) | 5 (5) |
| Donor | |
| Median age, y (range) | 34 (2-65) |
| Male (%) | 56 (52) |
| Female donor to male recipient (%) | 31 (29) |
| Sex match (%) | 56 (52) |
| ABO match (%) | 72 (67) |
| ABO major incompatibility (%) | 17 (16) |
| Positive CMV serology (%) | 56 (55) |
| Transplantation | |
| Conditioning | |
| TBI + CY ± others (%) | 32 (30) |
| Bu + CY (%) | 58 (54) |
| GVHD prophylaxis | |
| CSA + MTX (%) | 94 (88) |
| CSA + MTX + other (%) | 6 (6) |
| CSA ± corticosteroids (%) | 7 (6) |
| Graft composition | |
| Median NC, 108/kg (range) | 2.4 (0.2-8.1) |
| Median CD34, 106/kg (range) n = 83 | 3.6 (0.07-17.9) |
Disease stage is based on International Bone Marrow Transplant Registry classification.
NC indicates nucleated cells.