Peripheral blood hematology
| . | Wild type . | ST3Gal-I′ . | ST3Gal-II′ . | ST3Gal-III′ . | ST3Gal-IV′ . |
|---|---|---|---|---|---|
| WBC (cells/μL) | 6263 ± 2646 | 6510 ± 2217 | 5027 ± 1600 | 6993 ± 1644 | 5454 ± 2732 |
| Neutrophils (%) | 15 ± 10 | 24 ± 14 | 12 ± 6 | 9 ± 4 | 18 ± 16 |
| Lymphocytes (%) | 79 ± 12 | 60 ± 20 | 81 ± 8 | 85 ± 5 | 74 ± 17 |
| Monocytes (%) | 3.9 ± 3.4 | 13.9 ± 8.3* | 3.2 ± 2.1 | 3.1 ± 2.6 | 5.8 ± 3.9 |
| Eosinophils (%) | 1.3 ± 1.9 | 0.3 ± 0.3 | 1.1 ± 1.7 | 1.6 ± 1.6 | 1.3 ± 1.4 |
| Basophils (%) | 1.2 ± 1.6 | 2.3 ± 2.1 | 2.8 ± 1.9 | 1.5 ± 1.5 | 1.0 ± 2.2 |
| RBC (× 106/mL) | 8.9 ± 0.5 | 8.4 ± 1.7 | 8.9 ± 0.6 | 8.5 ± 0.6 | 8.5 ± 0.6 |
| PLT (× 103/mL) | 1021 ± 281 | 406 ± 191* | 893 ± 300 | 1000 ± 192 | 363 ± 182* |
| MPV (fL) | 5.7 ± 1.4 | 11 ± 2.3* | 6.9 ± 0.4 | 6.9 ± 0.4 | 8.4 ± 2.5* |
| Sample size, n | 64 | 14 | 10 | 19 | 45 |
| . | Wild type . | ST3Gal-I′ . | ST3Gal-II′ . | ST3Gal-III′ . | ST3Gal-IV′ . |
|---|---|---|---|---|---|
| WBC (cells/μL) | 6263 ± 2646 | 6510 ± 2217 | 5027 ± 1600 | 6993 ± 1644 | 5454 ± 2732 |
| Neutrophils (%) | 15 ± 10 | 24 ± 14 | 12 ± 6 | 9 ± 4 | 18 ± 16 |
| Lymphocytes (%) | 79 ± 12 | 60 ± 20 | 81 ± 8 | 85 ± 5 | 74 ± 17 |
| Monocytes (%) | 3.9 ± 3.4 | 13.9 ± 8.3* | 3.2 ± 2.1 | 3.1 ± 2.6 | 5.8 ± 3.9 |
| Eosinophils (%) | 1.3 ± 1.9 | 0.3 ± 0.3 | 1.1 ± 1.7 | 1.6 ± 1.6 | 1.3 ± 1.4 |
| Basophils (%) | 1.2 ± 1.6 | 2.3 ± 2.1 | 2.8 ± 1.9 | 1.5 ± 1.5 | 1.0 ± 2.2 |
| RBC (× 106/mL) | 8.9 ± 0.5 | 8.4 ± 1.7 | 8.9 ± 0.6 | 8.5 ± 0.6 | 8.5 ± 0.6 |
| PLT (× 103/mL) | 1021 ± 281 | 406 ± 191* | 893 ± 300 | 1000 ± 192 | 363 ± 182* |
| MPV (fL) | 5.7 ± 1.4 | 11 ± 2.3* | 6.9 ± 0.4 | 6.9 ± 0.4 | 8.4 ± 2.5* |
| Sample size, n | 64 | 14 | 10 | 19 | 45 |
Hematology values are presented as means ± SD. WBC, white blood cells; RBC, red blood cells; PLT, platelet; MPV, mean platelet volume. Significant differences between appropriate wild-type or heterozygous controls and/genotypes are indicated. (*)P < .01. Wild-type values are pooled as littermates of all mutant genotypes.