Incidence of severe (grades 3-4) side effects from imatinib mesylate therapy
| Side effect . | No. patients (%) . |
|---|---|
| Nausea, vomiting | 1 (4) |
| Diarrhea | 0 |
| Skin rashes | — |
| Drug-related | 0 |
| GVHD-related | 3 (11) |
| Muscle cramps | 1 (4) |
| Bone or joint aches | 2 (7) |
| Fluid retention | 3 (10) |
| Periorbital | 2 (7) |
| Lower extremities | 2 (7) |
| Weight gain greater than 10% | 1 (4) |
| Liver dysfunction | 5 (18) |
| Other effects | — |
| Drug fever | 1 (4) |
| Infection | 1 (4) |
| Granulocytopenia lower than 0.5 × 109/L | 6 of 14 (43) |
| Thrombocytopenia lower than 50 × 109/L | 4 of 15 (27) |
| Side effect . | No. patients (%) . |
|---|---|
| Nausea, vomiting | 1 (4) |
| Diarrhea | 0 |
| Skin rashes | — |
| Drug-related | 0 |
| GVHD-related | 3 (11) |
| Muscle cramps | 1 (4) |
| Bone or joint aches | 2 (7) |
| Fluid retention | 3 (10) |
| Periorbital | 2 (7) |
| Lower extremities | 2 (7) |
| Weight gain greater than 10% | 1 (4) |
| Liver dysfunction | 5 (18) |
| Other effects | — |
| Drug fever | 1 (4) |
| Infection | 1 (4) |
| Granulocytopenia lower than 0.5 × 109/L | 6 of 14 (43) |
| Thrombocytopenia lower than 50 × 109/L | 4 of 15 (27) |