Table 1.

PMN transendothelial migration time and junction protein open time

VE-cadherinPECAM-1
TtToTtTo
Culture     
 Bicellular boundary 48.2 ± 3.3 (22) 50.9 ± 3.1 (22) 44.7 ± 2.6 (19) 46.3 ± 2.9 (19) 
 Multicellular corner 49.0 ± 1.7 (79) 52.9 ± 1.7 (79) 47.4 ± 1.9 (54) 48.9 ± 1.9 (54) 
Tissue     
 Bicellular boundary 79 ± 9 (16) 86 ± 9 (16) 79 ± 11 (13) 88 ± 11 (13) 
 Multicellular corner 81 ± 5 (58) 86 ± 5 (58) 79 ± 5 (45) 87 ± 5 (45) 
VE-cadherinPECAM-1
TtToTtTo
Culture     
 Bicellular boundary 48.2 ± 3.3 (22) 50.9 ± 3.1 (22) 44.7 ± 2.6 (19) 46.3 ± 2.9 (19) 
 Multicellular corner 49.0 ± 1.7 (79) 52.9 ± 1.7 (79) 47.4 ± 1.9 (54) 48.9 ± 1.9 (54) 
Tissue     
 Bicellular boundary 79 ± 9 (16) 86 ± 9 (16) 79 ± 11 (13) 88 ± 11 (13) 
 Multicellular corner 81 ± 5 (58) 86 ± 5 (58) 79 ± 5 (45) 87 ± 5 (45) 

Numbers in parentheses represent the number of transmigration events counted. Tt, transmigration time (seconds) determined by tracing the morphologic changes of PMNs; To, junction protein open time (seconds) determined by tracing the movements of either junction protein

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