Signs and symptoms that suggest an underlying bleeding disorder
With the acceptance that menorrhagia is generally defined as >80 mL of blood loss per menstrual cycle, the following associations were agreed on as being indicative of menorrhagia |
Soaking through a pad or tampon within 1 h |
Soaking through bedclothes |
Below normal ferritin |
Anemia |
Pictorial blood assessment chart score >100 |
An underlying bleeding disorder should be considered if any of the following are present: |
Menorrhagia since menarche |
Family history of a bleeding disorder |
Personal history of 1, but usually several, of the following symptoms: |
Epistaxis (generally bilateral epistaxis, >10 min duration, once in the last year possibly necessitating packing or cautery) |
Notable bruising without injury (and >2 cm in diameter) |
Minor wound bleeding (ie, from trivial cuts lasting for >5 min) |
Bleeding of oral cavity or gastrointestinal tract without an obvious anatomic lesion |
Prolonged or excessive bleeding after dental extraction |
Unexpected postsurgical bleeding |
Hemorrhage from ovarian cysts or corpus luteum, possibly with accompanying pain during ovulation (termed mittleschmerz) |
Hemorrhage that required blood transfusion |
Postpartum hemorrhage (PPH), especially delayed PPH (after 24 h; no response to conventional management of menorrhagia) |
With the acceptance that menorrhagia is generally defined as >80 mL of blood loss per menstrual cycle, the following associations were agreed on as being indicative of menorrhagia |
Soaking through a pad or tampon within 1 h |
Soaking through bedclothes |
Below normal ferritin |
Anemia |
Pictorial blood assessment chart score >100 |
An underlying bleeding disorder should be considered if any of the following are present: |
Menorrhagia since menarche |
Family history of a bleeding disorder |
Personal history of 1, but usually several, of the following symptoms: |
Epistaxis (generally bilateral epistaxis, >10 min duration, once in the last year possibly necessitating packing or cautery) |
Notable bruising without injury (and >2 cm in diameter) |
Minor wound bleeding (ie, from trivial cuts lasting for >5 min) |
Bleeding of oral cavity or gastrointestinal tract without an obvious anatomic lesion |
Prolonged or excessive bleeding after dental extraction |
Unexpected postsurgical bleeding |
Hemorrhage from ovarian cysts or corpus luteum, possibly with accompanying pain during ovulation (termed mittleschmerz) |
Hemorrhage that required blood transfusion |
Postpartum hemorrhage (PPH), especially delayed PPH (after 24 h; no response to conventional management of menorrhagia) |
Content modified from James et al.12