Histologic comparison of glomerulonephritis after PBSC transplantation
| Group . | Mice . | No. . | Glomerular damage . |
|---|---|---|---|
| Control | BXSB→BXSB | 2 | 3.6 ± 0.24-150 |
| Prevention | BALB/c→BXSB | 5 | 1.5 ± 0.44-150,4-151 |
| BALB/c+BXSB→BXSB | 5 | 1.3 ± 0.34-150,4-151 | |
| Transfer | BXSB→BALB/c | 4 | 1.9 ± 1.0 |
| BXSB+BALB/c→BALB/c | 4 | 2.0 ± 0.9 |
| Group . | Mice . | No. . | Glomerular damage . |
|---|---|---|---|
| Control | BXSB→BXSB | 2 | 3.6 ± 0.24-150 |
| Prevention | BALB/c→BXSB | 5 | 1.5 ± 0.44-150,4-151 |
| BALB/c+BXSB→BXSB | 5 | 1.3 ± 0.34-150,4-151 | |
| Transfer | BXSB→BALB/c | 4 | 1.9 ± 1.0 |
| BXSB+BALB/c→BALB/c | 4 | 2.0 ± 0.9 |
Recipient BXSB (BALB/c) mice were killed at 48 weeks of age. The degree of glomerular damage was scored from 1 to 4 as described in “Materials and methods.” Values are presented as mean ± SD.
P < .05 for the control mice versus each of the 2 prevention groups.
P = .2 for BALB/c→BXSB prevention mice versus BALB/c+BXSB→BXSB prevention mice.