Table 6.

Numbers of nucleated cells and anti-SRBC PFCs of spleen cells of PBSC chimeras

GroupMiceNo.Spleen cells, no. × 107Anti-SRBC PFCs, /5 × 105spleen cells6-150
Control BALB/c 13.0 ± 1.7 253 ± 54.9 
 BXSB 80.0 ± 10.5 3 ± 2.8 
 BXSB→BXSB 46.8 ± 19.0 18 ± 4.6 
 BALB/c→B6 8.5 ± 4.0 8 ± 2.1 
Prevention BALB/c→BXSB 10.6 ± 0.6 27 ± 18.76-151 
 BALB/c+BXSB→BXSB 17.7 ± 2.1 90 ± 23.56-151 
GroupMiceNo.Spleen cells, no. × 107Anti-SRBC PFCs, /5 × 105spleen cells6-150
Control BALB/c 13.0 ± 1.7 253 ± 54.9 
 BXSB 80.0 ± 10.5 3 ± 2.8 
 BXSB→BXSB 46.8 ± 19.0 18 ± 4.6 
 BALB/c→B6 8.5 ± 4.0 8 ± 2.1 
Prevention BALB/c→BXSB 10.6 ± 0.6 27 ± 18.76-151 
 BALB/c+BXSB→BXSB 17.7 ± 2.1 90 ± 23.56-151 

Primary anti-SRBC antibody productions were tested when the recipients were 48 weeks old.

F6-150

Each mouse was injected intraperitoneally with 0.5 mL 2% spleen blood cells (SRBCs). At 5 days later, primary PFC responses were assessed. The results are expressed as the mean ± SD.

F6-151

P < .05 for BALB/c→BXSB versus BALB/c+BXSB→BXSB prevention mice.

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