Table 1. Clinicohematologic... | American Society of Hematology

Table 1.

Clinicohematologic characteristics and levels ofFLT3/ITD in paired diagnostic and first relapse samples in adult AML patients with single mutations

Patient	Age/sex	FAB subtype	Chromosome/genetic abnormality	Length of FLT3/ITD (bp)	% leukemic blasts in BM		FLT3/ITD level (%)		%FLT3/ITD expression by RT-PCR
Patient	Age/sex	FAB subtype	Chromosome/genetic abnormality	Length of FLT3/ITD (bp)	Diagnosis	Relapse	Diagnosis	Relapse	Diagnosis	Relapse
1	38/F	M5a	46,XX	69	95.3	97.3	39.2	100	31.4	93.8
2	66/F	M2	46,XX	33	51.6	94.0	15.8	22.2	20.5	38.4
3	56/F	M2	46,XX	60	69.4	73.0	39.1	64.6	38.6	97.1
4	50/M	M2	46,XY	33	49.0	36.2	10.5	50.8	NA	96.9
5	29/F	M2	ND	36	66.2	56.4	29.8	39.8	NA	93.2
6	67/M	M4	46,XY	33	83.6	46.0	32.8	60.7	33.1	NA
7	21/M	M0	ND	30	94.3	88.8	56.5	58.2	57.3	57.4
8	32/M	M2	46,XY	15	51.6	52.2	44.5	37.9	34.4	45.4
9	34/M	M5a	46,XY	45	96.2	51.1	33.1	10.2	36.8	80.0
10	61/F	M3	46,XX,t(15;17)(q22;q21)	30	90.2	84.4	9.8	0	8.1	0
11	45/M	M3	46,XY,add(6)(p22),t(15;17) (q22;q21)	21	84.1	59.0	0	50.2	0	41.7
12	47/F	M2	46,XX	165	42.6	90.8	0	16.5	0	40.5
13	60/M	M2	ND	63	77.0	64.8	0	42.1	0	19.4
14	60/M	M2	ND	24	73.6	98.7	0	88.6	0	100.0
15	41/F	M1	46,XX	63	92.8	73.0	0	31.7	0	46.8
16	36/F	M2	46,XX	24	92.5	39.2	0	35.5	0	70.9
17	48/F	M2	46,XX, partial tandem duplication ofMLL	63	65.8	42.8	0	1.0	0	1.5

Patient	Age/sex	FAB subtype	Chromosome/genetic abnormality	Length of FLT3/ITD (bp)	% leukemic blasts in BM		FLT3/ITD level (%)		%FLT3/ITD expression by RT-PCR
Patient	Age/sex	FAB subtype	Chromosome/genetic abnormality	Length of FLT3/ITD (bp)	Diagnosis	Relapse	Diagnosis	Relapse	Diagnosis	Relapse
1	38/F	M5a	46,XX	69	95.3	97.3	39.2	100	31.4	93.8
2	66/F	M2	46,XX	33	51.6	94.0	15.8	22.2	20.5	38.4
3	56/F	M2	46,XX	60	69.4	73.0	39.1	64.6	38.6	97.1
4	50/M	M2	46,XY	33	49.0	36.2	10.5	50.8	NA	96.9
5	29/F	M2	ND	36	66.2	56.4	29.8	39.8	NA	93.2
6	67/M	M4	46,XY	33	83.6	46.0	32.8	60.7	33.1	NA
7	21/M	M0	ND	30	94.3	88.8	56.5	58.2	57.3	57.4
8	32/M	M2	46,XY	15	51.6	52.2	44.5	37.9	34.4	45.4
9	34/M	M5a	46,XY	45	96.2	51.1	33.1	10.2	36.8	80.0
10	61/F	M3	46,XX,t(15;17)(q22;q21)	30	90.2	84.4	9.8	0	8.1	0
11	45/M	M3	46,XY,add(6)(p22),t(15;17) (q22;q21)	21	84.1	59.0	0	50.2	0	41.7
12	47/F	M2	46,XX	165	42.6	90.8	0	16.5	0	40.5
13	60/M	M2	ND	63	77.0	64.8	0	42.1	0	19.4
14	60/M	M2	ND	24	73.6	98.7	0	88.6	0	100.0
15	41/F	M1	46,XX	63	92.8	73.0	0	31.7	0	46.8
16	36/F	M2	46,XX	24	92.5	39.2	0	35.5	0	70.9
17	48/F	M2	46,XX, partial tandem duplication ofMLL	63	65.8	42.8	0	1.0	0	1.5

ND indicates not done; NA, not available.