Table 1. Reactivity patterns of... | American Society of Hematology

Table 1.

Reactivity patterns of monoclonal anti-D

Pattern^*		Anti-D tested, n^†	Partial D
1-9	1-37	Anti-D tested, n^†	DNB^‡	DII^1-153	DNU^‡	DIV type 3^‡
1	1	1	+	+	+	−
1	2	2	+	+	+	−
2	3	2	+	+	+	−
2	4	1	+	+	+	−
3	5	3	+	+	+	−
4	6	1	−	−	+	−
5	7	2	+	+	+	+
5	10	4	+	+	+	+
5	11	1	+	+	+	+
6/7	12	4	+	+	+	+
6/7	13	6	+	+	+	+
6/7	15/16	8	+	+	+	+
		4	+	+	+	−
6/7	17	8	+	+	+	+
6/7	18	6	+	+	+	+
		1	−	+	+	+
6/7	20/21	3	+	+	+	+
		1	+	+	+	−
8	22	2	+	+	+	+
9	23	3	+	−	+	−
		2	−	−	+	−
		2	+	−	−	−
N/A	31	2	−	+	+	−
N/A	32	1	+	+	+	+
N/A	33	1	+	+	+	+
N/A	34	1	+	+	−	−
N/A	35	1	+	+	+	−
N/A	36	3	+	+	+	−
		1	+	+	−	−
N/A	37	5	+	+	+	+

Pattern^*		Anti-D tested, n^†	Partial D
1-9	1-37	Anti-D tested, n^†	DNB^‡	DII^1-153	DNU^‡	DIV type 3^‡
1	1	1	+	+	+	−
1	2	2	+	+	+	−
2	3	2	+	+	+	−
2	4	1	+	+	+	−
3	5	3	+	+	+	−
4	6	1	−	−	+	−
5	7	2	+	+	+	+
5	10	4	+	+	+	+
5	11	1	+	+	+	+
6/7	12	4	+	+	+	+
6/7	13	6	+	+	+	+
6/7	15/16	8	+	+	+	+
		4	+	+	+	−
6/7	17	8	+	+	+	+
6/7	18	6	+	+	+	+
		1	−	+	+	+
6/7	20/21	3	+	+	+	+
		1	+	+	+	−
8	22	2	+	+	+	+
9	23	3	+	−	+	−
		2	−	−	+	−
		2	+	−	−	−
N/A	31	2	−	+	+	−
N/A	32	1	+	+	+	+
N/A	33	1	+	+	+	+
N/A	34	1	+	+	−	−
N/A	35	1	+	+	+	−
N/A	36	3	+	+	+	−
		1	+	+	−	−
N/A	37	5	+	+	+	+

N/A indicates not applicable; +, a normal or weak positive result; and −, a negative result.

Pattern is as described previously by Lomas et al24 (1-9) and Scott21 (1-37).

†

A complete listing of the antibodies was published previously13 (Table 2). The following antibodies failed to agglutinate DNB: LOR17-6C7 (epD6), P3F20 (epD18), HIRO-7, HIRO-8 (epD23), NAU6-1G6, and NOU (epD31). In addition, the reactivity of the following anti-Ds differed from that of the majority assigned to the respective epitope: D-90/7, SAL20-12D5, LHM50/2B, BIRMA-DG3 (epD15/16), as well as VOL-3F6 (epD20/21) did not agglutinate DIV type 3; LHM77/64, BIRMA-D6 (epD23), and NAU6-4D5 (epD36) did not agglutinate DNU.

‡

The DNB pattern was established with samples RIR-2 and RIR-3 and the DNU pattern with red cells of the original DNU donor.14 The DIV type 3 data are a reevaluation of the original pattern using a CcDee DIV type 3 donor from our local population.

F1-153

The results depicted for D category II were determined by Scott21 and are shown for comparison.

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