Table 1. The diagnosis of polycythemia... | American Society of Hematology

Table 1.

The diagnosis of polycythemia vera

1903^*	1971^†
Erythrocytosis Cyanosis Splenomegaly	Elevated red cell mass Normal arterial 0₂saturation Splenomegaly Plus any 2 below if no splenomegaly Leukocytosis greater than 12 000/μL Thrombocytosis greater than 400 000/μL Leukocyte alkaline phosphatase greater than 100 Serum B₁₂ greater than 900 pg/mL or unbound B₁₂ binding capacity greater than 2200 pg/mL

1903^*	1971^†
Erythrocytosis Cyanosis Splenomegaly	Elevated red cell mass Normal arterial 0₂saturation Splenomegaly Plus any 2 below if no splenomegaly Leukocytosis greater than 12 000/μL Thrombocytosis greater than 400 000/μL Leukocyte alkaline phosphatase greater than 100 Serum B₁₂ greater than 900 pg/mL or unbound B₁₂ binding capacity greater than 2200 pg/mL

From Osler.71

From Wasserman.72