TCR-Vβ use in cord-blood mononuclear cells of uninfected (mean % ± SEM, n = 6-9) or congenitally infected newborns (individual data of 3 newborns)
. | CD8+ T cells . | CD4+ T cells . | ||||||
---|---|---|---|---|---|---|---|---|
Uninfected newborns . | Congenitally infected newborns . | Uninfected newborns . | Congenitally infected newborns . | |||||
1 . | 2 . | 3 . | 1 . | 2 . | 3 . | |||
Vβ3 | 5.8 ± 1.0* | 0.7 | 1.2 | 6.6 | 4.9 ± 0.8 | 7.6 | 4.2 | 2.5 |
Vβ5 | 3.2 ± 0.2 | 7.5† | 3.5 | 2.4 | 2.2 ± 0.1 | 3.4† | 2.6 | 1.6 |
Vβ11 | 0.8 ± 0.1 | 1.1 | 0.6 | 0.8 | 0.8 ± 0.0 | 2.0† | 1.0† | 0.6 |
Vβ13.1 | 3.4 ± 0.3 | 13.5† | 13.5† | 2.8 | 3.4 ± 0.3 | 7.1† | 3.4 | 2.8 |
Vβ14 | 6.8 ± 0.7 | 9.0 | 4.5 | 4.1 | 2.9 ± 0.1 | 2.4 | 3.0 | 2.5 |
Vβ16 | 0.8 ± 0.1 | 0.8 | 0.6 | 1.2† | 0.7 ± 0.1 | 0.3 | 0.9 | 0.5 |
Vβ17 | 5.6 ± 0.6 | 23.9† | 3.0 | 5.2 | 5.1 ± 0.2 | 5.3 | 4.6 | 3.8 |
Vβ18 | 0.6 ± 0.2 | 1.4 | 0.3 | 0.2 | 0.8 ± 0.1 | 1.5† | 1.1 | 0.8 |
Vβ22 | 4.5 ± 0.6 | 1.1 | 11.7† | 2.2 | 3.9 ± 0.4 | 5.5 | 5.1 | 4.0 |
. | CD8+ T cells . | CD4+ T cells . | ||||||
---|---|---|---|---|---|---|---|---|
Uninfected newborns . | Congenitally infected newborns . | Uninfected newborns . | Congenitally infected newborns . | |||||
1 . | 2 . | 3 . | 1 . | 2 . | 3 . | |||
Vβ3 | 5.8 ± 1.0* | 0.7 | 1.2 | 6.6 | 4.9 ± 0.8 | 7.6 | 4.2 | 2.5 |
Vβ5 | 3.2 ± 0.2 | 7.5† | 3.5 | 2.4 | 2.2 ± 0.1 | 3.4† | 2.6 | 1.6 |
Vβ11 | 0.8 ± 0.1 | 1.1 | 0.6 | 0.8 | 0.8 ± 0.0 | 2.0† | 1.0† | 0.6 |
Vβ13.1 | 3.4 ± 0.3 | 13.5† | 13.5† | 2.8 | 3.4 ± 0.3 | 7.1† | 3.4 | 2.8 |
Vβ14 | 6.8 ± 0.7 | 9.0 | 4.5 | 4.1 | 2.9 ± 0.1 | 2.4 | 3.0 | 2.5 |
Vβ16 | 0.8 ± 0.1 | 0.8 | 0.6 | 1.2† | 0.7 ± 0.1 | 0.3 | 0.9 | 0.5 |
Vβ17 | 5.6 ± 0.6 | 23.9† | 3.0 | 5.2 | 5.1 ± 0.2 | 5.3 | 4.6 | 3.8 |
Vβ18 | 0.6 ± 0.2 | 1.4 | 0.3 | 0.2 | 0.8 ± 0.1 | 1.5† | 1.1 | 0.8 |
Vβ22 | 4.5 ± 0.6 | 1.1 | 11.7† | 2.2 | 3.9 ± 0.4 | 5.5 | 5.1 | 4.0 |