Table 8. Treatment outcome of patients... | American Society of Hematology

Table 8.

Treatment outcome of patients with sole trisomy 8 and of those with trisomy 8 accompanying other aberrations

Trisomy 8	No. of patients	% CR	P^7-150	5-y CIR (SE)	P^7-150	% 5-y OS (95% CI)	P^7-150
With t(9;11)	10	100	.04	0.50 (0.17)	.45	60 (31-83)	.07
With inv(16) or t(16;16)	12	83	.36	0.52 (0.18)	.16	57 (31-80)	.009
Sole	41	61	.39	0.77 (0.09)	.54	12 (5-27)	.049
With 1 other abnormality	26	50	.09	0.77 (0.13)	.05	8 (3-20)	.002
In complex karyotype with at least 3 abnormalities	26	23	<.001	1.00 (0.17)	.001	4 (1-13)	<.001

Trisomy 8	No. of patients	% CR	P^7-150	5-y CIR (SE)	P^7-150	% 5-y OS (95% CI)	P^7-150
With t(9;11)	10	100	.04	0.50 (0.17)	.45	60 (31-83)	.07
With inv(16) or t(16;16)	12	83	.36	0.52 (0.18)	.16	57 (31-80)	.009
Sole	41	61	.39	0.77 (0.09)	.54	12 (5-27)	.049
With 1 other abnormality	26	50	.09	0.77 (0.13)	.05	8 (3-20)	.002
In complex karyotype with at least 3 abnormalities	26	23	<.001	1.00 (0.17)	.001	4 (1-13)	<.001

Abbreviations are explained in the footnote to Table 5.

For comparison with normal cytogenetics (Tables 4 and 5).