Table 1.

Effect of IVIG on the elimination of 7E3

Dose of IVIG, g/kgClearance of 7E3, mL h−1kg−1*t1/2, h†
0 0.78 ± 0.09 79 ± 11 
0.4 1.28 ± 0.19‡ 68 ± 6 
1 1.37 ± 0.281-153 54 ± 17‡ 
2 1.85 ± 0.191-153 56 ± 10 
Dose of IVIG, g/kgClearance of 7E3, mL h−1kg−1*t1/2, h†
0 0.78 ± 0.09 79 ± 11 
0.4 1.28 ± 0.19‡ 68 ± 6 
1 1.37 ± 0.281-153 54 ± 17‡ 
2 1.85 ± 0.191-153 56 ± 10 

Noncompartmental techniques were used to determine each parameter value. Values are listed as mean ± SD (n = 3-4).

*

ANOVA, P < .001.

†

ANOVA, P = .06.

‡

Dunnett posttest, P < .05 relative to control.

F1-153

Dunnett posttest, P < .01 relative to control.

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