Table 1. Derivation of Mac-1 Gr-1... | American Society of Hematology

Table 1.

Derivation of Mac-1⁺Gr-1⁺splenocytes on D+7 after transplantation

	Graft composition without G-CSF		Graft composition with G-CSF
	HSCs, n = 10	HSC + CMP/GMP, n = 5	HSCs, n = 7	HSC + CMP/GMP, n = 6
Total splenocytes	111.1 ± 12.9	181.5 ± 12.9^*	63.4 ± 7.5	300.8 ± 40.0^*,^†
Total CD45⁺splenocytes	82.7 ± 14.0	105.0 ± 26.2	43.1 ± 7.5	142.0 ± 20.6^*,^†
Total Mac-1⁺Gr-1⁺	13.3 (16%)	29.8 (28%)^*	3.7 (8.6%)	29.5 (21%)^*,^†
Derivation
Donor HSCs	11.6 ± 4.2	4.7 ± 1.2	2.5 ± 0.7	6.4 ± 1.4^†
Donor CMP/GMP	—	20.1 ± 4.9	—	14.9 ± 1.8
Host	1.6 ± 0.3	5.0 ± 1.6	1.2 ± 0.5	8.2 ± 5.5^†

	Graft composition without G-CSF		Graft composition with G-CSF
	HSCs, n = 10	HSC + CMP/GMP, n = 5	HSCs, n = 7	HSC + CMP/GMP, n = 6
Total splenocytes	111.1 ± 12.9	181.5 ± 12.9^*	63.4 ± 7.5	300.8 ± 40.0^*,^†
Total CD45⁺splenocytes	82.7 ± 14.0	105.0 ± 26.2	43.1 ± 7.5	142.0 ± 20.6^*,^†
Total Mac-1⁺Gr-1⁺	13.3 (16%)	29.8 (28%)^*	3.7 (8.6%)	29.5 (21%)^*,^†
Derivation
Donor HSCs	11.6 ± 4.2	4.7 ± 1.2	2.5 ± 0.7	6.4 ± 1.4^†
Donor CMP/GMP	—	20.1 ± 4.9	—	14.9 ± 1.8
Host	1.6 ± 0.3	5.0 ± 1.6	1.2 ± 0.5	8.2 ± 5.5^†

Data are expressed as mean cell counts ± SEM (×10⁴). Values in parentheses indicate the percentage of the CD45⁺ population that was Mac-1⁺Gr-1⁺.

Significantly different from HSCs without G-CSF (P < .05).

Significantly different from HSCs with G-CSF (P < .05).