Clinical characteristics of patients analyzed late after allogeneic SCT
Variable . | Patients, n = 18 . |
---|---|
Age, y, median (range) | 43.5 (17-58) |
Patient sex | |
Male | 9 |
Female | 9 |
Underlying disease | |
CML | 5 |
AML | 4 |
ALL | 4 |
NHL | 4 |
MDS | 1 |
Patient/donor HCMV-serologic status | |
+/+ | 9 |
−/+ | 1 |
+/− | 4 |
−/− | 4 |
Conditioning regimen | |
TBI/CY ± VP16 | 11 |
BU/CY ± ARA-C | 5 |
TBI/FLU/CY | 2 |
Type of donor | |
HLA-identical family donor | 10 |
Matched unrelated | 6 |
Mismatch family | 2 |
Acute GVHD | |
Grades 0/I | 11 |
Grade II | 4 |
Grades III/IV | 3 |
Chronic GVHD | |
None/limited disease | 12 |
Extensive disease | 6 |
Variable . | Patients, n = 18 . |
---|---|
Age, y, median (range) | 43.5 (17-58) |
Patient sex | |
Male | 9 |
Female | 9 |
Underlying disease | |
CML | 5 |
AML | 4 |
ALL | 4 |
NHL | 4 |
MDS | 1 |
Patient/donor HCMV-serologic status | |
+/+ | 9 |
−/+ | 1 |
+/− | 4 |
−/− | 4 |
Conditioning regimen | |
TBI/CY ± VP16 | 11 |
BU/CY ± ARA-C | 5 |
TBI/FLU/CY | 2 |
Type of donor | |
HLA-identical family donor | 10 |
Matched unrelated | 6 |
Mismatch family | 2 |
Acute GVHD | |
Grades 0/I | 11 |
Grade II | 4 |
Grades III/IV | 3 |
Chronic GVHD | |
None/limited disease | 12 |
Extensive disease | 6 |
CML indicates chronic myeloid leukemia; AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; NHL, non-Hodgkin lymphoma; MDS, myelodysplastic syndrome; HCMV, human cytomegalovirus; TBI, total body irradiation; CY, cyclophosphamide; VP16, etoposide; BU, busulfan; FLU, fludarabine; and ARA-C, cytosinarabinoside.