Clinical characteristics of patients included for generation of CLL-cell cDNA libraries
| Patient . | Age, y . | Sex . | Stage . | Time from diagnosis to collection, y . | Prior treatment . | White blood count, × 109/L . | Autoimmune phenomena . | Isolated antigens . |
|---|---|---|---|---|---|---|---|---|
| 1 | 61 | M | Rai I/BinetA | 5 | None | 48 | None | 3 |
| 2 | 45 | M | Rai II/BinetA | 1 | None | 72 | None | 6 |
| 3 | 50 | M | Rai II/BinetA | 3 | None | 28 | None | 4 |
| 4 | 46 | F | Rai II/BinetB | 3 | None | 54 | None | 1 |
| 5 | 50 | M | Rai IV/BinetC | 8 | None | 466 | AIHA, ITP | 1 |
| Patient . | Age, y . | Sex . | Stage . | Time from diagnosis to collection, y . | Prior treatment . | White blood count, × 109/L . | Autoimmune phenomena . | Isolated antigens . |
|---|---|---|---|---|---|---|---|---|
| 1 | 61 | M | Rai I/BinetA | 5 | None | 48 | None | 3 |
| 2 | 45 | M | Rai II/BinetA | 1 | None | 72 | None | 6 |
| 3 | 50 | M | Rai II/BinetA | 3 | None | 28 | None | 4 |
| 4 | 46 | F | Rai II/BinetB | 3 | None | 54 | None | 1 |
| 5 | 50 | M | Rai IV/BinetC | 8 | None | 466 | AIHA, ITP | 1 |
Purified CLL cells were used for generation of 5 different cDNA expression libraries. Patient characteristics, clinical data, and number of isolated clones are shown. One antigen, KW-5, was selected independently from 2 different libraries.
AIHA indicates autoimmune hemolytic anemia; ITP, idiopathic thrombocytopenic purpura.