ALK-1QD– and ALK-5TD–regulated genes in HMVEC-d's 15 hours after infection
| Gene/protein name (accession number) . | ALK-1QD/β-gal* . | ALK-5TD/β-gal* . | |
|---|---|---|---|
| cDNA array . | rtPCR . | cDNA array . | |
| Up-regulated genes | |||
| MIC-1/GDF-15 (Q99988) | 7.95 | 5.01 | 1.06 |
| GRP78/BiP (P11021) | 4.46 | ND | 2.23 |
| Ubiquitin (Q9BWD6) | 3.92 | ND | 1.01 |
| BMPRII (Q13873) | 2.41 | ND | 1.97 |
| SODI (P00441) | 2.07 | ND | 0.89 |
| Glycyl tRNA synthetase (P41250) | 1.98 | ND | 0.80 |
| MAP1B (P46821) | 1.91 | ND | 1.07 |
| p21/waf1 (P38936) | 1.75 | 1.75 | 0.70 |
| Down-regulated genes | |||
| Zyxin (Q15942) | 0.46 | 0.62 | 0.84 |
| β-actin (Q9UE89) | 0.47 | 0.52 | 0.93 |
| Paxillin (P49023) | 0.51 | 0.53 | 0.80 |
| c-myc (P01106) | 0.51 | 0.48 | 1.12 |
| HMG-I (P17096) | 0.59 | ND | ND |
| Gene/protein name (accession number) . | ALK-1QD/β-gal* . | ALK-5TD/β-gal* . | |
|---|---|---|---|
| cDNA array . | rtPCR . | cDNA array . | |
| Up-regulated genes | |||
| MIC-1/GDF-15 (Q99988) | 7.95 | 5.01 | 1.06 |
| GRP78/BiP (P11021) | 4.46 | ND | 2.23 |
| Ubiquitin (Q9BWD6) | 3.92 | ND | 1.01 |
| BMPRII (Q13873) | 2.41 | ND | 1.97 |
| SODI (P00441) | 2.07 | ND | 0.89 |
| Glycyl tRNA synthetase (P41250) | 1.98 | ND | 0.80 |
| MAP1B (P46821) | 1.91 | ND | 1.07 |
| p21/waf1 (P38936) | 1.75 | 1.75 | 0.70 |
| Down-regulated genes | |||
| Zyxin (Q15942) | 0.46 | 0.62 | 0.84 |
| β-actin (Q9UE89) | 0.47 | 0.52 | 0.93 |
| Paxillin (P49023) | 0.51 | 0.53 | 0.80 |
| c-myc (P01106) | 0.51 | 0.48 | 1.12 |
| HMG-I (P17096) | 0.59 | ND | ND |
ND indicates not determined.
Mean of 2 experiments.