Nonhematologic and noninfectious toxicity
| . | No. of patients (%) (n = 31) . | |
|---|---|---|
| Grade 1 and/or 2 . | Grade 3 and/or 4 . | |
| Chills | 12 (39) | — |
| Fever | 10 (32) | 1 (3) |
| Erythema | 8 (26) | — |
| Edema | 5 (16) | — |
| Fatigue | 4 (13) | — |
| Diarrhea | 3 (10) | — |
| Dyspnea | 3 (10) | — |
| Headache | 3 (10) | — |
| Insomnia | 3 (10) | — |
| Nausea | 3 (10) | — |
| Pain | 2 (6) | 1 (3) |
| Tachycardia | 2 (6) | 1 (3) |
| . | No. of patients (%) (n = 31) . | |
|---|---|---|
| Grade 1 and/or 2 . | Grade 3 and/or 4 . | |
| Chills | 12 (39) | — |
| Fever | 10 (32) | 1 (3) |
| Erythema | 8 (26) | — |
| Edema | 5 (16) | — |
| Fatigue | 4 (13) | — |
| Diarrhea | 3 (10) | — |
| Dyspnea | 3 (10) | — |
| Headache | 3 (10) | — |
| Insomnia | 3 (10) | — |
| Nausea | 3 (10) | — |
| Pain | 2 (6) | 1 (3) |
| Tachycardia | 2 (6) | 1 (3) |
Other events that occured only in one patient were allergic reaction, brachycardia, hypotension, thrombosis, athralgia, weight gain, anorexia, cholelithiasis, rectal fistula, gastric ulcer, hemorrhoids, agitation, conjunctivitis, glaucoma, nephrolithiasis, and intracerebral bleeding.