Table 5.

The course of C4 and albumin serum levels in the studied patients after rituximab therapy

Median valueIncrease less than
25% or unchanged
Increase 25%
or greater
NormalizationNotes
Months +3 +6 +1 to +5 +6 +1 to +5 +6 +1 to +5 +6 — 
C4 mg/dL 85-150 85-150 6 of 14 7 of 14 3 of 14 3 of 14 5 of 14 4 of 14 Normalized at month +6 in patients 3, 4, 14, 15  
Albumin g/L 3.7 3.95-150 4.05-150 12 of 15 14 of 15 0 of 15 0 of 15 3 of 15 1 of 15 Normalized in patients 5 (+3 and +6) and 1, 11 (+3) 
Median valueIncrease less than
25% or unchanged
Increase 25%
or greater
NormalizationNotes
Months +3 +6 +1 to +5 +6 +1 to +5 +6 +1 to +5 +6 — 
C4 mg/dL 85-150 85-150 6 of 14 7 of 14 3 of 14 3 of 14 5 of 14 4 of 14 Normalized at month +6 in patients 3, 4, 14, 15  
Albumin g/L 3.7 3.95-150 4.05-150 12 of 15 14 of 15 0 of 15 0 of 15 3 of 15 1 of 15 Normalized in patients 5 (+3 and +6) and 1, 11 (+3) 

— indicates not applicable; C4, complement fraction (decreased if < 10 mg/dL); albumin, low at baseline (<3.5 g/L) in 4 of 15 patients (patients 1, 5, 8, and 11).

F5-150

P ≤ .05.

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