Variables predictive for molecular outcome (univariate analysis)
| Prognostic factor . | HR . | 95% CI . | P* . |
|---|---|---|---|
| VHunmutated | 4.8 | 1.9-11.1 | .0006 |
| del 11q− present | 4.9 | 4.3-71.1 | < .0001 |
| Both VHunmutated and del 11q− present (versus VHmutated) | 6.2 | 3.2-63.4 | .0005 |
| LDT less than 12 mo | 4.2 | 1.4-10.7 | .007 |
| Lymphocyte count 50 × 109/L | 2.5 | 1.1-6.2 | .02 |
| Prognostic factor . | HR . | 95% CI . | P* . |
|---|---|---|---|
| VHunmutated | 4.8 | 1.9-11.1 | .0006 |
| del 11q− present | 4.9 | 4.3-71.1 | < .0001 |
| Both VHunmutated and del 11q− present (versus VHmutated) | 6.2 | 3.2-63.4 | .0005 |
| LDT less than 12 mo | 4.2 | 1.4-10.7 | .007 |
| Lymphocyte count 50 × 109/L | 2.5 | 1.1-6.2 | .02 |
Variables not predictive included sex, age, time from diagnosis to transplantation, timing of transplantation (first-line or salvage), and Binet stage.
Log-rank test.