Table 4.

Seropositivity rate of historical control populations

GroupCMV seropositivity rateOR or OSReference
Group 1Group 2
Personnel providing services to disabled children Before exposure to mentally retarded children Seronegative persons converting in 1 y — De Schryver et al15 
 Educators (n = 283) 15.9% 1.03% — — 
 Nurses (n = 294) 18.4% 1.42% — — 
Kindergarten employees     
 Teachers/administrators (n = 494) Childless women: 16.4% ≥ 1 child at home: 33.7% Raising children: 2.25 Kiss et al16 
   Kindergarten teacher: 1.54  
Couples receiving artificial insemination (n = 433) Women in couples: 37% Men in couples: 31% No effect of age on seropositivity rate Greenhalgh et al17 
Health care workers caring for:    Sobaszek et al18 
 Pediatric inpatients (n = 283) 44.5% — — — 
 Immunosuppressed adults (n = 117) 43.6% — — — 
Home child care providers (n = 132) Overall baseline rate: 57.6% Annual seroconversion rate: 6.8% Caring for child < 2 y: 2.37 Bale et al19 
Cared for child <2 y: 67%  Employed > 6 y: 3.27  
Cared for child >2 y: 46%    
Japanese pregnant women (n = 573) Aged < 25 y: 67.7% Aged > 40 y: 85.7% — Nishimura et al20 
Men attending STD clinic (n = 430) Heterosexual: 42% Homosexual: 80% — Berry et al21 
Homosexual men living in San Francisco (n = 1123) 96% — — Dylewski et al22 
HIV+/−adolescents HIV+ females: 78.5% HIVfemales: 61.4% — Holland et al23 
 HIV+ males: 79.7% HIV males: 50%   
German case-control subjects    Rothenbacher et al24 
 Subjects with CAD (n = 312) 54.5% — — — 
 Blood donors (n = 479) 49.9% — — — 
Renal transplantation recipients
(n = 47 146) 
Age > 60 y: 80% Blacks: 71% — Hirata et al25 
 Asians: 80% Whites: 56%   
BMT recipients from unrelated donor
(n = 125) 
60.8% — OS at 3 years: Kroger et al26 
   CMV+ pts: 29%  
   CMV pts: 70%  
GroupCMV seropositivity rateOR or OSReference
Group 1Group 2
Personnel providing services to disabled children Before exposure to mentally retarded children Seronegative persons converting in 1 y — De Schryver et al15 
 Educators (n = 283) 15.9% 1.03% — — 
 Nurses (n = 294) 18.4% 1.42% — — 
Kindergarten employees     
 Teachers/administrators (n = 494) Childless women: 16.4% ≥ 1 child at home: 33.7% Raising children: 2.25 Kiss et al16 
   Kindergarten teacher: 1.54  
Couples receiving artificial insemination (n = 433) Women in couples: 37% Men in couples: 31% No effect of age on seropositivity rate Greenhalgh et al17 
Health care workers caring for:    Sobaszek et al18 
 Pediatric inpatients (n = 283) 44.5% — — — 
 Immunosuppressed adults (n = 117) 43.6% — — — 
Home child care providers (n = 132) Overall baseline rate: 57.6% Annual seroconversion rate: 6.8% Caring for child < 2 y: 2.37 Bale et al19 
Cared for child <2 y: 67%  Employed > 6 y: 3.27  
Cared for child >2 y: 46%    
Japanese pregnant women (n = 573) Aged < 25 y: 67.7% Aged > 40 y: 85.7% — Nishimura et al20 
Men attending STD clinic (n = 430) Heterosexual: 42% Homosexual: 80% — Berry et al21 
Homosexual men living in San Francisco (n = 1123) 96% — — Dylewski et al22 
HIV+/−adolescents HIV+ females: 78.5% HIVfemales: 61.4% — Holland et al23 
 HIV+ males: 79.7% HIV males: 50%   
German case-control subjects    Rothenbacher et al24 
 Subjects with CAD (n = 312) 54.5% — — — 
 Blood donors (n = 479) 49.9% — — — 
Renal transplantation recipients
(n = 47 146) 
Age > 60 y: 80% Blacks: 71% — Hirata et al25 
 Asians: 80% Whites: 56%   
BMT recipients from unrelated donor
(n = 125) 
60.8% — OS at 3 years: Kroger et al26 
   CMV+ pts: 29%  
   CMV pts: 70%  

OR, odds ratio; OS, overall survival; STD, sexually transmitted disease; BMT, bone marrow transplant; CAD, coronary artery disease; and pts, patients.  —  indicates not applicable.

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