IgVH mutational frequency considering the productive rearrangement in 96 MCL cases, in relation to the main clinical features at presentation
| . | 0% . | Frequency of IgVHsomatic mutation . | ||
|---|---|---|---|---|
| . | More than 0% . | More than 2% . | More than 5% . | |
| Total | 29 | 67 | 28 | 13 |
| Splenomegaly at diagnosis | 5/26 | 21/26 | 11/26 | 5/26 |
| Splenic primary MCL | 1/5 | 4/5 | 3/5 | 3/5* |
| PB/BM infiltration | 13/51 | 38/51 | 17/51 | 9/51 |
| I/II CS | 4/9 | 5/9 | 1/9 | 1/9 |
| Waldeyer | 1/7 | 6/7 | 0/7† | 0/7 |
| Intestinal | 0/7 | 7/7 | 3/7 | 0/7 |
| Diffuse/nodular/MZ pattern | 6/13/3 | 20/18/6 | 8/6/3 | 2/3/1 |
| Blastoid | 5/14 | 9/14 | 6/14 | 3/14 |
| i-GC Cyclin D1+ cells | 5/20 | 14/20 | 6/20 | 3/20 |
| . | 0% . | Frequency of IgVHsomatic mutation . | ||
|---|---|---|---|---|
| . | More than 0% . | More than 2% . | More than 5% . | |
| Total | 29 | 67 | 28 | 13 |
| Splenomegaly at diagnosis | 5/26 | 21/26 | 11/26 | 5/26 |
| Splenic primary MCL | 1/5 | 4/5 | 3/5 | 3/5* |
| PB/BM infiltration | 13/51 | 38/51 | 17/51 | 9/51 |
| I/II CS | 4/9 | 5/9 | 1/9 | 1/9 |
| Waldeyer | 1/7 | 6/7 | 0/7† | 0/7 |
| Intestinal | 0/7 | 7/7 | 3/7 | 0/7 |
| Diffuse/nodular/MZ pattern | 6/13/3 | 20/18/6 | 8/6/3 | 2/3/1 |
| Blastoid | 5/14 | 9/14 | 6/14 | 3/14 |
| i-GC Cyclin D1+ cells | 5/20 | 14/20 | 6/20 | 3/20 |