Plasma concentrations of angiogenic factors in patients treated with R115777
| . | Plasma concentration, median, pg/mL . | ||
|---|---|---|---|
| Baseline . | Day 7 . | Day 14 . | |
| VEGF | 97.9 | 108.2 | 122.8 |
| bFGF | 16.3 | 11.7 | 14.1 |
| HGF | 926.8 | 933.9 | 881.6 |
| TNF-α | 7.16 | 7.06 | 7.42 |
| IFN-α | 6.62 | 6.68 | 6.56 |
| VEGF responders3-150 | 668.8 | 213.1 | 173.1 |
| VEGF nonresponders | 78.8 | 96.6 | 108.3 |
| . | Plasma concentration, median, pg/mL . | ||
|---|---|---|---|
| Baseline . | Day 7 . | Day 14 . | |
| VEGF | 97.9 | 108.2 | 122.8 |
| bFGF | 16.3 | 11.7 | 14.1 |
| HGF | 926.8 | 933.9 | 881.6 |
| TNF-α | 7.16 | 7.06 | 7.42 |
| IFN-α | 6.62 | 6.68 | 6.56 |
| VEGF responders3-150 | 668.8 | 213.1 | 173.1 |
| VEGF nonresponders | 78.8 | 96.6 | 108.3 |
P = .002. All other P's were not significant. (P's are based on change in plasma concentrations from baseline.)