Direct target genes of C/EBPα
| Accession no. . | Gene title . | Fold change . | |
|---|---|---|---|
| Exp 2 h β-ES . | Exp 8 h β-ES+CHX . | ||
| M31166 | TSG-14 | 4.59 | 2.30 |
| Y00630 | Plasminogen activator inhibitor 2 (PAI-2) | 3.48 | 1.74 |
| U64197 | Small inducible cytokine member 20 (SCYA20) | 3.03 | 1.52 |
| X89214 | Haptoglobin-related protein | 2.64 | 1.74 |
| D10040 | Fatty-acid coenzyme A ligase, long-chain 2 | 2.64 | 1.74 |
| D10923 | HM74 | 2.46 | 3.48 |
| M31165 | TNF α-induced P6 | 2.30 | 1.62 |
| D14520 | Kruppel-like factor 5 | 2.30 | 1.87 |
| V01512 | c-fos | 2.14 | 1.52 |
| X77956 | Id1 | 2.14 | 1.52 |
| U27467 | BCL2-related protein A1 | 2.00 | 2.00 |
| X97324 | Adipophilin | 2.00 | 2.14 |
| J04076 | EGR2 | 2.00 | 2.14 |
| S77812 | VEGF receptor | 1.87 | 1.62 |
| U22961 | Albumin | 1.87 | 5.28 |
| X76648 | Glutaredoxin (thioltransferase) | 1.87 | 1.62 |
| M63835 | IgG Fc receptor 1 gene | 1.87 | 1.62 |
| AF079167 | Oxidized LDL receptor 1 | 1.87 | 2.14 |
| Y08136 | ASM-like phosphodiesterase 3a | 1.87 | 1.74 |
| U05861 | Aldo-keto reductase C2 (AKR1C2) | 1.74 | 2.14 |
| M81750 | Myeloid cell nuclear differentiation antigen | 1.74 | 1.52 |
| X04430 | Interleukin-6 | 1.74 | 1.52 |
| U01134 | Soluble VEGF receptor (sflt) | 1.62 | 1.87 |
| AF084523 | Cellular repressor of E1A-stimulated genes (CREG) | 1.62 | 1.62 |
| D10925 | Chemokine (C-C motif) receptor 1 | 1.62 | 1.62 |
| L06797 | Chemokine (C-X-C motif), receptor 4 (CXCR4) | 1.62 | 1.62 |
| U04636 | PTGS2 | 1.52 | 1.87 |
| HG620-HT620 | Tyrosine phosphatase, epsilon | 1.52 | 1.74 |
| X69910 | p63 transmembrane protein | 1.52 | 1.52 |
| X54134 | Protein tyrosine phosphatase ɛ | 1.52 | 1.87 |
| X75346 | MAPKAPK2 | −1.52 | −1.62 |
| V00505 | Hemoglobin, delta | −1.52 | −1.62 |
| Z50781 | Delta sleep-inducing peptide (DSIPI) | −1.52 | −1.62 |
| AF070528 | Lymphoid tissue lymphoma translocation gene 1 | −1.52 | −1.52 |
| U68485 | Bridging integrator 1 (BIN1) | −1.52 | −1.52 |
| S77154 | Nuclear receptor 4A2 | −1.52 | −1.87 |
| M32334 | ICAM2 | −1.52 | −1.52 |
| Z35278 | PEBP2aC1 | −1.62 | −1.52 |
| AB016811 | ADP-ribosylation factorlike protein | −1.62 | −1.62 |
| AF051325 | SCAP | −1.74 | −2.30 |
| M22637 | Lymphoblastic leukemia derived seq. 1 (LYL1) | −1.74 | −1.62 |
| X75918 | NOT | −1.87 | −2.46 |
| X15606 | ICAM2 | −1.87 | −1.62 |
| Accession no. . | Gene title . | Fold change . | |
|---|---|---|---|
| Exp 2 h β-ES . | Exp 8 h β-ES+CHX . | ||
| M31166 | TSG-14 | 4.59 | 2.30 |
| Y00630 | Plasminogen activator inhibitor 2 (PAI-2) | 3.48 | 1.74 |
| U64197 | Small inducible cytokine member 20 (SCYA20) | 3.03 | 1.52 |
| X89214 | Haptoglobin-related protein | 2.64 | 1.74 |
| D10040 | Fatty-acid coenzyme A ligase, long-chain 2 | 2.64 | 1.74 |
| D10923 | HM74 | 2.46 | 3.48 |
| M31165 | TNF α-induced P6 | 2.30 | 1.62 |
| D14520 | Kruppel-like factor 5 | 2.30 | 1.87 |
| V01512 | c-fos | 2.14 | 1.52 |
| X77956 | Id1 | 2.14 | 1.52 |
| U27467 | BCL2-related protein A1 | 2.00 | 2.00 |
| X97324 | Adipophilin | 2.00 | 2.14 |
| J04076 | EGR2 | 2.00 | 2.14 |
| S77812 | VEGF receptor | 1.87 | 1.62 |
| U22961 | Albumin | 1.87 | 5.28 |
| X76648 | Glutaredoxin (thioltransferase) | 1.87 | 1.62 |
| M63835 | IgG Fc receptor 1 gene | 1.87 | 1.62 |
| AF079167 | Oxidized LDL receptor 1 | 1.87 | 2.14 |
| Y08136 | ASM-like phosphodiesterase 3a | 1.87 | 1.74 |
| U05861 | Aldo-keto reductase C2 (AKR1C2) | 1.74 | 2.14 |
| M81750 | Myeloid cell nuclear differentiation antigen | 1.74 | 1.52 |
| X04430 | Interleukin-6 | 1.74 | 1.52 |
| U01134 | Soluble VEGF receptor (sflt) | 1.62 | 1.87 |
| AF084523 | Cellular repressor of E1A-stimulated genes (CREG) | 1.62 | 1.62 |
| D10925 | Chemokine (C-C motif) receptor 1 | 1.62 | 1.62 |
| L06797 | Chemokine (C-X-C motif), receptor 4 (CXCR4) | 1.62 | 1.62 |
| U04636 | PTGS2 | 1.52 | 1.87 |
| HG620-HT620 | Tyrosine phosphatase, epsilon | 1.52 | 1.74 |
| X69910 | p63 transmembrane protein | 1.52 | 1.52 |
| X54134 | Protein tyrosine phosphatase ɛ | 1.52 | 1.87 |
| X75346 | MAPKAPK2 | −1.52 | −1.62 |
| V00505 | Hemoglobin, delta | −1.52 | −1.62 |
| Z50781 | Delta sleep-inducing peptide (DSIPI) | −1.52 | −1.62 |
| AF070528 | Lymphoid tissue lymphoma translocation gene 1 | −1.52 | −1.52 |
| U68485 | Bridging integrator 1 (BIN1) | −1.52 | −1.52 |
| S77154 | Nuclear receptor 4A2 | −1.52 | −1.87 |
| M32334 | ICAM2 | −1.52 | −1.52 |
| Z35278 | PEBP2aC1 | −1.62 | −1.52 |
| AB016811 | ADP-ribosylation factorlike protein | −1.62 | −1.62 |
| AF051325 | SCAP | −1.74 | −2.30 |
| M22637 | Lymphoblastic leukemia derived seq. 1 (LYL1) | −1.74 | −1.62 |
| X75918 | NOT | −1.87 | −2.46 |
| X15606 | ICAM2 | −1.87 | −1.62 |
Target genes of C/EBPα identified in the experiments using a 2-hour exposure to β-estradiol or an 8-hour exposure with addition of cycloheximide are listed. The criteria used for target gene analysis are as described in Table 1.