Table 1.

Phenotypic characteristics of human LV'VFas-modified T cells stimulated with anti-CD3 alone or with both anti-CD3 and anti-CD28

PhenotypePBLs, % mean (range) no stimulationLV'VFas-modified T cells, % mean (range)
Anti-CD3Anti-CD3 and anti-CD28
CD3+ T cells 66.2 (53.5-74.0) 88.3 (81.9-93.5) 97.3 (95.1-99.3) 
CD3+CD4+ T cells 58.0 (43.1-71.5) 26.4 (10.8-36.2) 47.6 (30.4-65.9) 
CD3+CD8+ T cells 39.3 (25.1-57.4) 69.9 (63.6-81.4) 48.7 (34.8-58.3) 
CD3+CD28+ T cells 74.2 (62.2-86.1) 43.9 (35.6-52.3) 88.6 (73.5-97.6) 
CD16+ T cells 12.8 (9.3-16.3) 10.4 (6.5-12.7) 1.2 (0.1-3.3) 
PhenotypePBLs, % mean (range) no stimulationLV'VFas-modified T cells, % mean (range)
Anti-CD3Anti-CD3 and anti-CD28
CD3+ T cells 66.2 (53.5-74.0) 88.3 (81.9-93.5) 97.3 (95.1-99.3) 
CD3+CD4+ T cells 58.0 (43.1-71.5) 26.4 (10.8-36.2) 47.6 (30.4-65.9) 
CD3+CD8+ T cells 39.3 (25.1-57.4) 69.9 (63.6-81.4) 48.7 (34.8-58.3) 
CD3+CD28+ T cells 74.2 (62.2-86.1) 43.9 (35.6-52.3) 88.6 (73.5-97.6) 
CD16+ T cells 12.8 (9.3-16.3) 10.4 (6.5-12.7) 1.2 (0.1-3.3) 

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