Phenotypic characteristics of human LV'VFas-modified T cells stimulated with anti-CD3 alone or with both anti-CD3 and anti-CD28
Phenotype . | PBLs, % mean (range) no stimulation . | LV'VFas-modified T cells, % mean (range) . | |
---|---|---|---|
Anti-CD3 . | Anti-CD3 and anti-CD28 . | ||
CD3+ T cells | 66.2 (53.5-74.0) | 88.3 (81.9-93.5) | 97.3 (95.1-99.3) |
CD3+CD4+ T cells | 58.0 (43.1-71.5) | 26.4 (10.8-36.2) | 47.6 (30.4-65.9) |
CD3+CD8+ T cells | 39.3 (25.1-57.4) | 69.9 (63.6-81.4) | 48.7 (34.8-58.3) |
CD3+CD28+ T cells | 74.2 (62.2-86.1) | 43.9 (35.6-52.3) | 88.6 (73.5-97.6) |
CD16+ T cells | 12.8 (9.3-16.3) | 10.4 (6.5-12.7) | 1.2 (0.1-3.3) |
Phenotype . | PBLs, % mean (range) no stimulation . | LV'VFas-modified T cells, % mean (range) . | |
---|---|---|---|
Anti-CD3 . | Anti-CD3 and anti-CD28 . | ||
CD3+ T cells | 66.2 (53.5-74.0) | 88.3 (81.9-93.5) | 97.3 (95.1-99.3) |
CD3+CD4+ T cells | 58.0 (43.1-71.5) | 26.4 (10.8-36.2) | 47.6 (30.4-65.9) |
CD3+CD8+ T cells | 39.3 (25.1-57.4) | 69.9 (63.6-81.4) | 48.7 (34.8-58.3) |
CD3+CD28+ T cells | 74.2 (62.2-86.1) | 43.9 (35.6-52.3) | 88.6 (73.5-97.6) |
CD16+ T cells | 12.8 (9.3-16.3) | 10.4 (6.5-12.7) | 1.2 (0.1-3.3) |