Basal superoxide level in CLL patients, n = 50
| Patients . | O2− . | n . | P . |
|---|---|---|---|
| Sex | .09* | ||
| Male | 24.5 ± 16.1 | 32 | |
| Female | 17.4 ± 8.8 | 18 | |
| RAI stage | .3186† | ||
| 0 | 17.5 ± 10.5 | 7 | |
| 1 | 19.8 ± 14.8 | 8 | |
| 2 | 22.0 ± 7.2 | 15 | |
| 3 | 12.5 ± 6.0 | 4 | |
| 4 | 27.2 ± 17.8 | 16 | |
| Prior treatment | .0056* | ||
| Yes | 27.4 ± 16.9 | 25 | |
| No | 16.5 ± 8.2 | 25 |
| Patients . | O2− . | n . | P . |
|---|---|---|---|
| Sex | .09* | ||
| Male | 24.5 ± 16.1 | 32 | |
| Female | 17.4 ± 8.8 | 18 | |
| RAI stage | .3186† | ||
| 0 | 17.5 ± 10.5 | 7 | |
| 1 | 19.8 ± 14.8 | 8 | |
| 2 | 22.0 ± 7.2 | 15 | |
| 3 | 12.5 ± 6.0 | 4 | |
| 4 | 27.2 ± 17.8 | 16 | |
| Prior treatment | .0056* | ||
| Yes | 27.4 ± 16.9 | 25 | |
| No | 16.5 ± 8.2 | 25 |
Primary leukemia cells were isolated from 50 patients with CLL and cultured in vitro for 24 hours. The basal superoxide levels were determined by flow cytometry analysis. Data are shown as the mean ± SD.
Statistic analysis using the Student t test.
Statistic analysis using ANOVA. P < .05 is considered statistically significant.