Table 1. Percentage of abnormal nuclei... | American Society of Hematology

Table 1.

Percentage of abnormal nuclei in each cell lineage of 4 patients with myelofibrosis with myeloid metaplasia studied with fluorescent in situ hybridization using probes to detect 13q− and 20q−

Patient	CD3⁺	CD19⁺	PMN	CD34⁺	CD61⁺	CD71⁺
1 del(13)(q12q21.2) in 20 of 20 metaphases	42	61	82	58	75	78
2 del(13)(q12q14) in 20 of 20 metaphases	6	13	90	51	94	88
3 del(20)(q13.1) in 20 of 20 metaphases	57	96	98	87	77	81
4 del(20)(q13.1) in 16 of 21 metaphases	21	30	86	36	67	57

Patient	CD3⁺	CD19⁺	PMN	CD34⁺	CD61⁺	CD71⁺
1 del(13)(q12q21.2) in 20 of 20 metaphases	42	61	82	58	75	78
2 del(13)(q12q14) in 20 of 20 metaphases	6	13	90	51	94	88
3 del(20)(q13.1) in 20 of 20 metaphases	57	96	98	87	77	81
4 del(20)(q13.1) in 16 of 21 metaphases	21	30	86	36	67	57

Each column represents T cells (CD3⁺), B cells (CD19⁺), neutrophils (PMN), myeloid progenitor cells (CD34⁺), megakaryocyte precursor cells (CD61⁺), and erythroid cells (CD71⁺). Normal ranges are < 9.5% for 13q− and < 11.5% for 20q−.

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