Table 2. Hematologic alterations in... | American Society of Hematology

Table 2.

Hematologic alterations in primary recipients with aberrant donor chimerism from experiments 1 and 2

Mouse no.^*	Detected abnormalities^† (time of analysis in months)
1	Splenomegaly (6)
2	None (6)
3	Pancytopenia, hypoplastic bone marrow, splenomegaly with abnormal architecture and increased proportion of immature myeloid cells (16)
4	Unexpected death (16)
5	Splenomegaly (16)
6	Bone marrow myeloid hyperplasia and myelofibrosis with immature appearing myeloid cells (16)

Mouse no.^*	Detected abnormalities^† (time of analysis in months)
1	Splenomegaly (6)
2	None (6)
3	Pancytopenia, hypoplastic bone marrow, splenomegaly with abnormal architecture and increased proportion of immature myeloid cells (16)
4	Unexpected death (16)
5	Splenomegaly (16)
6	Bone marrow myeloid hyperplasia and myelofibrosis with immature appearing myeloid cells (16)

Chimerism data illustrated in Figure 3.

Analyzed peripheral blood counts, bone marrow and spleen cellularity, spleen weight, and bone marrow and spleen histology.