Peripheral blood analysis of wild-type and Sca-1–null mice
| Hematologic parameter . | Sca-1+/+ . | Sca-1−/− . |
|---|---|---|
| WBC count, × 103/μL | 12.5 ± 0.2 | 12.2 ± 0.1 |
| RBC count, × 106/μL | 11.1 ± 0.1 | 11.1 ± 0.1 |
| Plt count, × 103/μL | 1021.2 ± 25.2* | 615.6 ± 18.5* |
| Hgb level, g/dL | 17.4 ± 0.1 | 17.6 ± 0.1 |
| Hct, % | 54.6 ± 0.2 | 54.2 ± 0.3 |
| Percentage of WBC count | ||
| Lymphocytes, % | 90.57 ± 0.14† | 92.20 ± 0.33† |
| Monocytes, % | 6.65 ± 0.47† | 5.69 ± 0.36† |
| Granulocytes, % | 2.78 ± 0.16† | 2.11 ± 0.23† |
| Hematologic parameter . | Sca-1+/+ . | Sca-1−/− . |
|---|---|---|
| WBC count, × 103/μL | 12.5 ± 0.2 | 12.2 ± 0.1 |
| RBC count, × 106/μL | 11.1 ± 0.1 | 11.1 ± 0.1 |
| Plt count, × 103/μL | 1021.2 ± 25.2* | 615.6 ± 18.5* |
| Hgb level, g/dL | 17.4 ± 0.1 | 17.6 ± 0.1 |
| Hct, % | 54.6 ± 0.2 | 54.2 ± 0.3 |
| Percentage of WBC count | ||
| Lymphocytes, % | 90.57 ± 0.14† | 92.20 ± 0.33† |
| Monocytes, % | 6.65 ± 0.47† | 5.69 ± 0.36† |
| Granulocytes, % | 2.78 ± 0.16† | 2.11 ± 0.23† |
Analysis was performed on 12-week-old mice, 15 for each genotype. The peripheral blood values were determined by means of a Becton-Dickinson veterinary hematologic analyzer.
WBCs indicates white blood cells; RBCs, red blood cells; Plts, platelets; and Hgb, hemoglobin.
Highly significant differences; P < .01.
Significant differences; P < .05.