Comparison of myeloid lineages in wild-type and Sca-1–null bone marrow
| Lineage . | Sca-1+/+, % . | Sca-1−/−, % . |
|---|---|---|
| Erythroblast | 14.87 ± 2.45 | 14.79 ± 2.31 |
| Granulocyte | 48.87 ± 2.01 | 46.04 ± 2.01 |
| Megakaryocyte | 7.42 ± 0.36* | 1.82 ± 1.49* |
| Monocyte | 2.90 ± 0.43 | 2.67 ± 0.31 |
| Lineage . | Sca-1+/+, % . | Sca-1−/−, % . |
|---|---|---|
| Erythroblast | 14.87 ± 2.45 | 14.79 ± 2.31 |
| Granulocyte | 48.87 ± 2.01 | 46.04 ± 2.01 |
| Megakaryocyte | 7.42 ± 0.36* | 1.82 ± 1.49* |
| Monocyte | 2.90 ± 0.43 | 2.67 ± 0.31 |
Data were obtained by flow cytometric analysis of myeloid lineages with the use of the following lineage-specific markers: TER119+ (erythroblast), CD11b+Gr-1+(granulocyte), CD41+CD61+ (megakaryocyte), and CD11b+Gr-1− (monocyte).
Highly significant differences; P < .01.