Sibships and clinical stroke
| . | No. HbSS siblings with stroke . | Total patients, no. . | Strokes, no. . | ||
|---|---|---|---|---|---|
| 0 . | 1 . | 2 . | |||
| HbSS siblings per family | |||||
| 2 | 145 | 30 | 8 | 366 | 46 |
| 3 | 16 | 2 | 2 | 60 | 6 |
| 4 | 3 | 0 | 0 | 12 | 0 |
| 5 | 1 | 0 | 0 | 5 | 0 |
| Total | 165 | 32 | 10 | 443 | 52 |
| . | No. HbSS siblings with stroke . | Total patients, no. . | Strokes, no. . | ||
|---|---|---|---|---|---|
| 0 . | 1 . | 2 . | |||
| HbSS siblings per family | |||||
| 2 | 145 | 30 | 8 | 366 | 46 |
| 3 | 16 | 2 | 2 | 60 | 6 |
| 4 | 3 | 0 | 0 | 12 | 0 |
| 5 | 1 | 0 | 0 | 5 | 0 |
| Total | 165 | 32 | 10 | 443 | 52 |
There were 207 sibships with more than one sibling with HbSS among the 2353 HbSS patients. There were 52 clinical strokes among the 443 HbSS patients in sibships, for a prevalence of 11.7% (95% confidence interval [CI], 9.6%-15.1%).