Table 1. Patient characteristics at time... | American Society of Hematology

Table 1.

Patient characteristics at time of diagnosis

Characteristics	All registered patients, n = 379	Intensified chemotherapy, n = 129	Myeloablative therapy, n = 132
Age in years, median (range)	55 (31-65)	55 (38-65)	56 (32-65)
Male/female	235/144	74/55	81/51
WHO performance
0-1	297	108	107
2-3	78	19	25
Not done	4	2	0
Stage (Salmon and Durie)
IIA	75	32	27
IIB	5	0	2
IIIA	259	89	93
IIIB	40	8	10
Monoclonal protein
IgA	98	40	34
IgG	215	70	78
IgD	9	3	3
LcD	42	11	11
Nonsecreting myeloma	15	5	6
Hemoglobin level less than or equal to 6.21 mM	136	49	39
Serum calcium greater than 2.65 mM	45	8	12
Serum LDH greater than ULN	55	23	14
Serum β₂-microglobulin
0-3	155	55	62
Greater than 3 mg/L	170	49	60
Not done	54	25	10
Bone marrow plasma cells
Less than or equal to 50%	221	75	79
Greater than 50%	125	38	45
Not done	33	16	8
Number of skeletal lesions
0	75	31	24
1-2	59	18	23
At least 3	243	80	85
Not done	2	0	0

Characteristics	All registered patients, n = 379	Intensified chemotherapy, n = 129	Myeloablative therapy, n = 132
Age in years, median (range)	55 (31-65)	55 (38-65)	56 (32-65)
Male/female	235/144	74/55	81/51
WHO performance
0-1	297	108	107
2-3	78	19	25
Not done	4	2	0
Stage (Salmon and Durie)
IIA	75	32	27
IIB	5	0	2
IIIA	259	89	93
IIIB	40	8	10
Monoclonal protein
IgA	98	40	34
IgG	215	70	78
IgD	9	3	3
LcD	42	11	11
Nonsecreting myeloma	15	5	6
Hemoglobin level less than or equal to 6.21 mM	136	49	39
Serum calcium greater than 2.65 mM	45	8	12
Serum LDH greater than ULN	55	23	14
Serum β₂-microglobulin
0-3	155	55	62
Greater than 3 mg/L	170	49	60
Not done	54	25	10
Bone marrow plasma cells
Less than or equal to 50%	221	75	79
Greater than 50%	125	38	45
Not done	33	16	8
Number of skeletal lesions
0	75	31	24
1-2	59	18	23
At least 3	243	80	85
Not done	2	0	0