Table 8.

Infections WHO grade 2-4 after intermediate-dose melphalan (IDM) cycles I and II (%) and myeloablative treatment

Treatment periodMyeloablative
therapy, n = 104
IDM cycle 1,
n = 254
IDM cycle 2,
n = 206
Septicemia 41 
Lung 15  
Ear/nose/throat 10  
GI tract 10  
GU tract 
Mucosa 10  
Skin 15 
Fever 10 22  
Other 9  
Maximum WHO 2 18 17 30  
Maximum WHO 3 12 12 39  
Maximum WHO 4 
Treatment periodMyeloablative
therapy, n = 104
IDM cycle 1,
n = 254
IDM cycle 2,
n = 206
Septicemia 41 
Lung 15  
Ear/nose/throat 10  
GI tract 10  
GU tract 
Mucosa 10  
Skin 15 
Fever 10 22  
Other 9  
Maximum WHO 2 18 17 30  
Maximum WHO 3 12 12 39  
Maximum WHO 4 

GI tract indicates gastrointestinal tract; and GU tract, genito-urethral tract.

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