Expression of candidate genes in CD34+ cells isolated from healthy individuals and patients with CML in M-BC
| Variable . | Healthy individuals (HP) . | M-BC . | HP versus M-BC . | ||||
|---|---|---|---|---|---|---|---|
| N . | Median . | Range . | N . | Median . | Range . | P . | |
| BAD | 12 | 5.7 | 3.0-11.7 | 37 | 4.4 | 0.6-39.0 | .209 |
| BAX | 12 | 5.8 | 2.3-9.2 | 37 | 10.4 | 0.9-81.4 | .015 |
| BCL-2 | 12 | 7.4 | 2.3-15.0 | 37 | 4.2 | 0.4-101.2 | .710 |
| BCL-XL | 12 | 4.6 | 1.3-8.5 | 36 | 10.7 | 3.3-144.5 | <.0005 |
| MDR-1 | 12 | 0.007 | 0.004-0.03 | 37 | 3.8 | 0.02-94.2 | <.0005 |
| MDM-2 | 12 | 20.1 | 8.0-84.2 | 36 | 1.8 | 0.1-1600 | .001 |
| MRP | 12 | 15.5 | 4.8-28.6 | 37 | 28.1 | 3.2-3586 | .003 |
| Survivin | 12 | 19.1 | 8.7-38.8 | 37 | 57.6 | 0.04-400 | .027 |
| Variable . | Healthy individuals (HP) . | M-BC . | HP versus M-BC . | ||||
|---|---|---|---|---|---|---|---|
| N . | Median . | Range . | N . | Median . | Range . | P . | |
| BAD | 12 | 5.7 | 3.0-11.7 | 37 | 4.4 | 0.6-39.0 | .209 |
| BAX | 12 | 5.8 | 2.3-9.2 | 37 | 10.4 | 0.9-81.4 | .015 |
| BCL-2 | 12 | 7.4 | 2.3-15.0 | 37 | 4.2 | 0.4-101.2 | .710 |
| BCL-XL | 12 | 4.6 | 1.3-8.5 | 36 | 10.7 | 3.3-144.5 | <.0005 |
| MDR-1 | 12 | 0.007 | 0.004-0.03 | 37 | 3.8 | 0.02-94.2 | <.0005 |
| MDM-2 | 12 | 20.1 | 8.0-84.2 | 36 | 1.8 | 0.1-1600 | .001 |
| MRP | 12 | 15.5 | 4.8-28.6 | 37 | 28.1 | 3.2-3586 | .003 |
| Survivin | 12 | 19.1 | 8.7-38.8 | 37 | 57.6 | 0.04-400 | .027 |