Table 6. Amino acid changes among... | American Society of Hematology

Table 6.

Amino acid changes among polymorphism and mutation

mtDNA gene	Patients with MDS												Healthy controls
mtDNA gene	9	10	11	12	13	14	15	16	17	18	No.	M	1	2	3	4	5	6	7	8	No.	M
ND1											0	0.0									0	0
ND2				^†	^†						2	0.2					^†		^†		2	0.3
COI											0	0.0					^†				1	0.1
COII				^††							2	0.2							^†		1	0.1
ATPase 8											0	0.0									0	0
ATPase 6			^††	^†							3	0.3	^†								1	0.1
COIII									^††		2	0.2		^†							1	0.1
ND3											0	0.3									0	0
ND4L											0	0.0									0	0
ND4											0	0.0									0	0
ND5						^†					1	0.1			^†			^†			2	0.3
ND6							^†				1	0.1									0	0
CYTB			^†			^†	^†		^††		5	0.5								^†	1	0.1
Total	0	0	3	4	1	2	2	0	4	0	16	1.6	1	1	1	0	2	1	2	1	9	1.1

mtDNA gene	Patients with MDS												Healthy controls
mtDNA gene	9	10	11	12	13	14	15	16	17	18	No.	M	1	2	3	4	5	6	7	8	No.	M
ND1											0	0.0									0	0
ND2				^†	^†						2	0.2					^†		^†		2	0.3
COI											0	0.0					^†				1	0.1
COII				^††							2	0.2							^†		1	0.1
ATPase 8											0	0.0									0	0
ATPase 6			^††	^†							3	0.3	^†								1	0.1
COIII									^††		2	0.2		^†							1	0.1
ND3											0	0.3									0	0
ND4L											0	0.0									0	0
ND4											0	0.0									0	0
ND5						^†					1	0.1			^†			^†			2	0.3
ND6							^†				1	0.1									0	0
CYTB			^†			^†	^†		^††		5	0.5								^†	1	0.1
Total	0	0	3	4	1	2	2	0	4	0	16	1.6	1	1	1	0	2	1	2	1	9	1.1

NC indicates noncoding region including hypervariable segments; M, mean; †, amino acid change; and 0, no amino acid change.